- Jeffrey Lazarus (ISGlobal)
- Funded by
- Gilead Sciences HCV-STAT Programme
The objective of this study is to eliminate hepatitis C virus (HCV) in the autonomous community of the Balearic Islands using the micro-elimination approach. The project aims to reach patients with a history of drug use who are treated in the different governmental and non-governmental addiction service centres, a mobile methadone unit, or are in prison, in order to test and link people who use drugs to HCV care.
The purpose of this project is to diagnose and treat hepatitis C in this key population group with a new model of care that simplifies the current diagnosis process and facilitates linkage to care and subsequent treatment initiation. In the different addiction services centres (Unitats de Conductes Addictives; UCAs), patients will be screened for HCV using a saliva-based rapid detection test (Oraquick®, Orasure Technologies Inc.,) to detect the presence of HCV antibodies (HCV Ab) followed by a dried blood spot (DBS) sample to confirm viremia (HCV-RNA).
Treatment will be prescribed by a hepatologists to those patients who are positive for the infection via telemedicine and will be delivered and administered at the same addiction services centres. To confirm the completion of treatment and sustained virologic response (SVR), in addition to possible reinfections, monitoring utilizing DBS will be carried out for up to a year after treatment completion.
The project commenced its testing activities in April 2021 and plans to scale up to all 17 sites throughout the year.
This project is led by the ISGlobal Health Systems Research group with Dr Àngels Vilella (Department of Gastroenterology, Hospital Universitari Son Llàtzer) and Dr Maria Buti (Hospital Vall d'Hebron) in collaboration with Hospital Universitari Son Espases, Hospital Comarcal d'Inca, Hospital Comarcal de Manacor (Mallorca), Hospital General Mateu Orfila (Menorca), and Hospital Can Misses (Ibiza), and is funded through the competitive research call HCV STAT, by Gilead Sciences.
Other projectsSee Past Projects
Hepatitis B Virus COMmunity Screening and Vaccination in Africans
Combating Bacterial Resistance In Europe
Application to medical devices
Combatting Bacterial Resistance in Europe - Carbapenem Resistance
Prioritising Antimicrobial Resistance: establishing an interdisciplinary International Research Partnership to tackle an evolving global health threat
An interdisciplinary International Research Partnership to tackle an evolving global health threat
Development of new metal-antibiotics against pathogens causing chronic infections in patients with cystic fibrosis.
New metal-antibiotics for patients with cystic fibrosis
Non-invasive ultrasound-based screening for meningitis: Proof-of concept in infants
Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique
Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals
Search for new target proteins and use of antibacterial or inhibitory peptides against resistance mechanisms in 'Acinetobacter baumannii'
Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique
Integrating and decentralizing diabetes and hypertension services in Africa
Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.
Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo
Pilot Study to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission
Cendea de Cizur
Conèixer la propagació. Entendre la protecció
A breakthrough device for the rapid detection of antimicrobial resistance
Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19
Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV
Close the Gap, Increase Access, Provide Adequate Therapy