- 01/01/2019 - 31/12/2023
- Morris Swertz
- H2020-EU and BBMRI-ERIC
- Página web
Rapid progress in information and biotechnologies offers the promise of better, personalized health strategies using rich phenotypic, environmental and molecular (omics) profiles of every individual. To capitalize on this great promise, key challenge is to relate these profiles to health and disease while accounting for high diversity in individuals, populations and environments. Both Europe and Canada have long-term investments in population-based prospective cohort studies providing essential longitudinal data. These data must be analysed in unison to reach statistical power, however, presently cohort data repositories are scattered, hard to search and integrate, and data protection and governance rules discourage central pooling.
EUCAN-Connect will enable large-scale integrated cohort data analysis for personalized and preventive healthcare across EU and Canada. This will be based on an open, scalable data platform for cohorts, researchers and networks, incorporating FAIR principles (Findable, Accessible, Interoperable, Reusable) for optimal reuse of existing data, and building on maturing federated technologies, with sensitive data kept locally and only results being shared and integrated, in line with key ELSI and governance guidelines. Widespread uptake will be promoted via beyond state-of-the-art research in close collaboration with leading cohort networks, focused on early-life origins of cardio-metabolic, developmental, musculoskeletal and respiratory health and disease impacting human life course.
To address challenges of sustainability and curation, we will deliver innovative solutions for distributed, low-cost data harvesting and preservation, community curation/harmonization, privacy protection, open source bioinformatics toolbox development, and international governance. EUCAN-Connect platform and collaborations will be coordinated through BBMRI-ERIC (EU) and Maelstrom Research (Canada) to sustain long-term benefits to science and citizens worldwide.
Otros proyectosVer proyectos pasados
Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe
Early-life stressors and LifeCycle health
Science and Technology in childhood Obesity Policy
Advancing Tools for Human Early Lifecourse Exposome Research and Translation
Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic
An integrative strategy of testing systems for identification of EDs related to metabolic disorders
Socioeconomic Status, Physical Activity, and Respiratory Health in Pregnant Women, Children, and Adolescents
Prenatal Exposure to Environmental Pollutants and Metabolic and Cardiovascular Health of the Teenagers
Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics
Developmental origins of child liver injury: the effect of early life environmental exposures
External and Internal Human Exposure in Urban EXposome
Entorno Urbano y Salud Cardiometabólica desde el Nacimiento hasta la Adolescencia
Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways
Exposures to light pollution and heat, and neurodevelopment in adolescents
Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility
Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development