CityExposomeCat
An Exposome Approach to Urban Health: Individualized Environmental Exposure Assessment in an Adults Population Cohort Study (GCAT)

- Duración
- 01/01/2018 - 31/12/2023
- Coordinador
- Manolis Kogevinas
- Financiadores
- ISCIII, FIS PI17/01388, FEDER
The CityExposomeCat project applied an “exposome” approach to a large cohort of adults in Catalonia (CAT) to evaluate environmental exposures and lifestyle factors that are related to urban settings, and examine their association with well being and major diseases (obesity, cardiometabolic, mental health). The project eventually expanded its objectives to include COVID-19 as a major outcome (see COVICAT cohort).
Exposome approaches ultimately allow the understanding of mechanisms of disease through the use of agnostic “omic” approaches and advanced technology in environmental epidemiology.
The CityExposomeCat focuses on the evaluation of environmental (e.g. air pollution) and lifestyle factors (e.g. sleep) and their association with health, while a companion project focuses on omics.
The GCAT cohort includes around 20,000 volunteer adults in Catalonia, mostly in urban areas that have completed a first round of questionnaires, provided biological samples and who can be identified in electronic primary and secondary health registers. Residences of all subjects were geocoded and a Geographic Information System (GIS) based approach was applied to evaluate environmental exposures (proximity to natural/green spaces, urban structure, air-pollution, noise, temperature and artificial light at night) using existing information (e.g. Urban Atlas, Landsat images).
A new follow-up was conducted in 6,000 subjects recovering additional information on environmental, lifestyle and incident health related outcomes.
A validation study was conducted in a subsample (unfortunately disrupted in March 2020 due to COVID-19) using advanced technologies for individual exposure assessment (e.g. actigraphs, light measurements) that should have allowed quantification of error and calibration of exposure assessment in the whole cohort.
Total Funding
64,463 €
Related Publications
The Links Between Air Pollution and COVID-19
Nuestro equipo
Coordinator
- Manolis Kogevinas Director científico de la distinción Severo Ochoa
ISGlobal Team
- Lourdes Arjona Técnica de investigación
- Gemma Castaño Staff Scientist
- Ana Espinosa Técnica Estadística
- Barbara Harding Assistant Research Professor
- Cristina O'Callaghan Gordo
- Anna Palomar Investigadora predoctoral
Otros proyectos
Ver proyectos pasadosCOVICAT
Cohorte Covid-19 en Cataluña
MCC-Spain
Estudio multi-caso control poblacional, incluyendo tumores de alta incidencia en España
ALEC
Aging Lungs in European Cohorts
PROactive
Physical Activity as a Crucial Patient Reported Outcome in COPD
QUALI-VERD
Social and environmental determinants of physical activity in patients with chronic obstructive pulmonary disease (COPD): a qualitative and quantitative epidemiological study
OMEGA-NET
Network on the Coordination and Harmonisation of European Occupational Cohorts
Global Assessment of Trihalomethanes in Drinking Water
POLLAR
Impact Of Pollution on Asthma and Rhinitis
EPHOR
Exposome Project for Health and Occupational Research
CORSAIR
Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors
VEIS
Valorización del Archivo Europeo del Genomas y Fenomas (EGA) para la Industria y la Sociedad
Mobilise-D
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
EARLY-ADAPT
Signs of Early Adaptation to Climate Change
AiguaBCN
Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing
Fotovoz
Las Voces de los Afectados por la Nefropatía Mesoamericana
Metabolomic Analysis as a Window into the Etiology of Mesoamerican Nephropathy
CALMA
Co-created educational programme for dyspnea-bearing patients and their caregivers
Cancer-Watch
Risk of colorectal and breast cancer with widespread drinking water chemical contaminants
CONTENT
Cohorte de COVID-19 en España: dinámica social, salud mental y desigualdades
EXPANSE
EXposome Powered tools for healthy living in urbAN SEttings
COVAIR-CAT
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia
Alimentación S2: por una dieta saludable y sostenible
Estudio sobre la exposición a nano y microplásticos a través del agua de consumo de Barcelona
¿Es mejor consumir el agua de grifo si queremos reducir la exposición a nano/micropláticos?
Laboratorio Ciudadano de Salud Urbana
Characterizing Oral Exposure to Nanoplastics and Microplastics
Characterization of Oral NMP Exposure
iGenCO
In-Depth Genomics and Cross-Omics Analysis for Undiagnosed Rare Diseases on a User-Friendly Collaborative Platform
TwinAir
Digital Twins Enabled Indoor Air Quality Management for Healthy Living
Subclinical Infections in Children and Long Term Health Effects
Infection acquisition in early life and health outcomes in childhood - MARATO TV3
UBDPOLICY
The Urban Burden of Disease Estimation for POLICY Making
Exposición prenatal a sustancias poli y perfluoradas en agua de consumo y neurodesarrollo en el inicio de la vida
Project Code: PI20/00829
TOLIFE
Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease