Asset Publisher

Chagas

NHEPACHA

New Tools for the Diagnosis and Evaluation of Chagas Disease

NHEPACHA is an Ibero-American network formed by 12 research groups from 9 countries working in the field of Chagas disease. The network was created to foster research activity and the exchange of knowledge and experiences and to build on the skills needed to develop new tools and biomarkers for the diagnosis, treatment, evaluation and management of Chagas disease and to improve existing ones.

Objectives

  • • Establish a research, development and innovation framework to identify potential new drugs as well as biomarkers that will aid in the diagnosis and management of Chagas disease and in the evaluation of new drugs in future clinical trials. Specific actions will include:
    • the identification of joint research topics
    • the fostering of academic exchanges among researchers
  • Promote the exchange of knowledge through:
    • training and work exchange programmes for members of the network
    • workshops
    • the production and dissemination of consensus statements and reviews on topics related to the goals of the network
  • Plan operational studies and multicentre clinical trials to test new tools and improve existing ones, through:
    • the design and coordination of research projects
    • the creation of a standardised database for monitoring patients with Chagas disease
    • the transfer of technology to the biomedical industry and national health systems

Members of the network

  • IMT-UCV (Instituto de Medicina Tropical, Universidad Central de Venezuela, Venezuela).
  • FIOCRUZ-IOC (Fundação Oswaldo Cruz – Instituto Oswaldo Cruz) Brazil.
  • ISGlobal (Barcelona Institute for Global Health), Spain
  • CIEI-PUCE (Centro de Investigación de Enfermedades Infecciosas de la Pontificia Universidad Católica del Ecuador), Ecuador.
  • UA-CIMPAT (Universidad de los Andes), Colombia.
  • IPBLN-CSIC. (Instituto de Parasitología y Biomedicina Lopez-Neyra), Spain.
  • CRISP –INSP (Centro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública), Mexico.
  • DNDi (Drugs for Neglected Diseases Initiative).
  • INGEBI (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular), Buenos Aires, Argentina.
  • CENDIE, (Centro Nacional de Diagnóstico e Investigación de Endemoepidemias), Argentina.
  • UMSS. (Universidad Mayor de San Simón), Bolivia.
  • HIGA (Hospital Interzonal General de Agudos Eva Perón, Sección Chagas, Servicio de Cardiología), Argentina
  • Fundación Mundo Sano, Argentina.

Other projects

See Past Projects

MESA

Sharing knowledge and catalyzing research towards a malaria-free world

RTS,S Vaccine Immunology Study

Study of immune correlates of protection against malaria after vaccination with RTS,S/AS01E: a comprehensive immunological arm of a Phase III double-blind, randomized, controlled multi-center trial

Euroleish.net

Control of Leishmaniasis. From bench to bedside and community

GREPIMER

Grup de recerca en patología importada i malaties emergents i re-emergents

TESEO

New chemotherapy regimens and biomarkers for Chagas Disease

BOHEMIA

Broad One Health Endectocide-based Malaria Intervention in Africa

ASINTMAL

Unravelling Disease Tolerance and Host Resistance in Afebrile 'P. falciparum' Infections: a Prospective Study in Mozambican Adults

ADAM

Malaria mass and focal drug administration to advance malaria elimination in Mozambique: accelerating programmatic implementation and policy translation

MULTIPLY

MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention

Science4Pandemics

Citizens engagement digital platform for collective intelligence in pandemics

HIDDENVIVAX

Novel organ-on-a-chip technology to study extracellular vesicles-mediated cryptic infections in Plasmodium vivax malaria

MENA Migrant Health

Transforming data collection and surveillance to drive migrant health research, care and policy

SexMal

Social affairs and sex in P. falciparum: implications for malaria elimination

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

SMART

Identifying Severe Malaria with a new Aptamer-based Rapid diagnostic Test

MalTransc

Transcriptional regulation of adaptation and developmental decisions in malaria parasites: from epigenetic variation to directed transcriptional responses

GenMoz

P. falciparum genomic intelligence in Mozambique