Research Programmes

Evaluation of Strategies for Yaws Eradication

Yaws eradication

Website
http://pian.isglobal.org

The Barcelona Institute for Global Health (ISGlobal) research team has developed the tools needed to definitively eradicate yaws from the planet: a diagnosis of yaws can now be confirmed using a new test based on a single drop of blood, and a single dose of azithromycin (an oral antibiotic) has been shown to be effective in curing the infection. http://www.who.int/yaws/photos/en/

The findings of the studies jump started the NTD community in action and prompted the World Health Organization (WHO) to target yaws for Global Eradication by 2020.

The objective of our new project is to evaluate the new WHO-strategy to stop yaws transmission which involves mass treatment with single dose oral azithromycin of the entire population. If the new strategy proves effective, countries will be free of the disease in one or two years after implementation.

What is the Ultimate Goal?

The goal is to eradicate yaws DEFINITIVELY WORLDWIDE in the short to medium term (10 years).

Yaws eradication will need a donation of 40 million treatments, with a cost of 0.50 Euro per treatment, and fundings to distribute the pill. Representatives of the countries where yaws is still endemic have made a commitment to fight this disease.

What is Yaws?

Documentary: War Against Yaws

The Broadcaster producer has started the filming of a documentary on Dr Oriol Mitjà's story: http://www.broadcaster.cat/pian

Project Funders

Newcrest Mining Limited

International SOS - Niugini

External links

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)61624-3/fulltext

http://www.who.int/yaws/photos/en/index2.html

http://www.theguardian.com/global-development/2014/feb/21/yaws-bacterial-skin-disease-who-donated-antibiotics

Our Team

ISGlobal Team

Other projects

See Past Projects

COMBACTE

Combating Bacterial Resistance In Europe

COMBACTE-CARE

Combatting Bacterial Resistance in Europe - Carbapenem Resistance

Xpatial-TB

Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique

WHIP3TB

Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals

VINCI

Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique

INTE-AFRICA

Integrating and decentralizing diabetes and hypertension services in Africa

AVATAR

Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.

COVID-PREG

Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo

AMR DetecTool

A breakthrough device for the rapid detection of antimicrobial resistance

ANTICOV

Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19

HBV-COMSAVA

Hepatitis B Virus COMmunity Screening and Vaccination in Africans

Stool4TB

Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV

Hep C Free Baleares

Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.

CAPTB

Close the Gap, Increase Access, Provide Adequate Therapy

STREESCO

Strengthening Epidemiological Surveillance in Benin and Burkina Faso for an Effective Response to COVID-19

COVAIR-CAT

Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia

TB-RECONNECT

Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status

SToolNIH

Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring