- 01/05/2019 - 30/04/2021
- Martine Vrijheid
- Instituto de Salud Carlos III
The understanding of how the urban environments affect health has been recognized as an urgent research priority. Urban environments are complex systems and there is a need to better understand how different domains of the urban environment interact with different individual behaviours and with a wide range of cardio-metabolic health outcomes during childhood.
UrbaMet aims to examine whether exposures in the urban environment influence cardio-metabolic health trajectories in children up to age 15 years in the longitudinal birth cohort study INMA, using state-of-the-art geographic information systems (GIS), biomarker, sensor, and imaging approaches to accurately assess exposures, outcomes, and mediators.
UrbaMet will start a new follow-up examination of the INMA children at 14-15 years of age (500 participants). As part of UrbaMet we will measure cardio-metabolic outcomes (pulse wave velocity, carotid intima media thickness, blood pressure, body mass index, body fat mass and distribution, lipid profiles, liver enzymes, and insulin resistance) in the children.
Urban environment measures (for the built environment, walkability, green spaces, food environment, and social environment) will be linked to geocodes using GIS. Data on mediating behaviours such as physical activity, sleep, diet, and commuting mode will be collected from the adolescents using novel sensors and computerised questionnaire tools. Stress levels will be measured through cortisol in hair.
UrbaMet is novel in that it will be the first longitudinal study to combine measurements of multiple urban environment domains during sensitive developmental time periods (early-life) with a comprehensive and longitudinal assessment of cardio-metabolic health and behavioural risk factors up until adolescence.
Martine Vrijheid Jefa del programa de Infancia y medio ambiente, Research Professor y Coordinadora de la Cohorte INMA-Sabadell
Otros proyectosVer proyectos pasados
Early Genetics Growth/Early Genetics and Lifecourse Epidemiology
Pregnancy and Childhood Epigenetics
Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe
Early-life stressors and LifeCycle health
Science and Technology in childhood Obesity Policy
Advancing Tools for Human Early Lifecourse Exposome Research and Translation
Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic
A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health
An integrative strategy of testing systems for identification of EDs related to metabolic disorders
Socioeconomic Status, Physical Activity, and Respiratory Health in Pregnant Women, Children, and Adolescents
Prenatal Exposure to Environmental Pollutants and Metabolic and Cardiovascular Health of the Teenagers
Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics
Developmental origins of child liver injury: the effect of early life environmental exposures
External and Internal Human Exposure in Urban EXposome
Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways
Exposures to light pollution and heat, and neurodevelopment in adolescents
Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility
Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development
Traffic-Related Air Pollution and Birth Weight: the Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status
Air Pollution and Birth Outcomes: Windows of Exposure and Health and Economic Impact Assessment
Radio Frequency Electromagnetic Fields, Noise, and Sleep Disorders in Adolescence
Prenatal Exposure to a Family of Short Half-Life Endocrine Disruptors, Dysregulation of the Hypothalamic–Pituitary–Adrenal Axis and Potential Implication for Child Neurodevelopment at Early Age
Caractérisation des usages et de l’exposition aux radiofréquences induite par les dispositifs de communication mobiles chez les enfants
Light at Night Exposure and Sleep Quality
Radiofrequency Electromagnetic Fields, Other Environmental Factors, and Development of the Embryo and Fetus
The Impact of Maternal-Fetal Steroid Metabolome Exposure on Child GROwth and Neurological Outcomes
The role of seafood and nut consumption on human neurodevelopment from pregnancy to adolescence