Duración
2012-2016
Coordinador
Paolo Vineis (Imperial College, London)
Financiadores
Comisión Europea

This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero.

Although environmental (i.e. non-genetic) exposures account for the majority of diseases currently there is no standard or systematic way to measure the influence of environmental exposures on health. This project will move the field forward by developing a personal exposure monitoring (PEM) system (including sensors, smartphones, geo-referencing, satellites) and collect data on individual external exposome as well as analysing biological samples (internal markers of external exposures) using multiple “omic” technologies. The search for the relationships between external exposures (as measured by PEM, which has not previously been used in large scale studies) and global profiles of molecular features (as measured by omics) in the same individuals constitutes a novel advance towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as ‘exposome-wide association studies’ (EWAS).

The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease.

Nuestro equipo

Investigador principal (IP)

  • Marius Joannes Nieuwenhuijsen
    Marius Joannes Nieuwenhuijsen

Equipo ISGlobal

Ver más

Otros proyectos

Ver proyectos pasados

ESCAPE

European Study of Cohorts for Air Pollution Effects

CHAI

Cardiovascular Health effects of Air pollution in Andhra Pradesh, India

ESAIRE

Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality

iMAP Barcelona

Estudio Internacional de la Mente, Actividades y Entornos Urbanos en Barcelona

HERA

Integrating Environment and Health Research: a Vision for the EU

EARLY-ADAPT

Signs of Early Adaptation to Climate Change

ACTIVID

Impacto de la crisis sanitaria de la COVID-19 en la Actividad Física y la Salud Mental en España

MCC-Spain

Estudio multi-caso control poblacional, incluyendo tumores de alta incidencia en España

ALEC

Aging Lungs in European Cohorts

PROactive

Physical Activity as a Crucial Patient Reported Outcome in COPD

QUALI-VERD

Social and environmental determinants of physical activity in patients with chronic obstructive pulmonary disease (COPD): a qualitative and quantitative epidemiological study

OMEGA-NET

Network on the Coordination and Harmonisation of European Occupational Cohorts

POLLAR

Impact Of Pollution on Asthma and Rhinitis

CORSAIR

Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors

VEIS

Valorización del Archivo Europeo del Genomas y Fenomas (EGA) para la Industria y la Sociedad

Mobilise-D

Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

COVICAT

Cohorte Covid-19 en Cataluña

AiguaBCN

Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing

Fotovoz

Las Voces de los Afectados por la Nefropatía Mesoamericana

CALMA

Co-created educational programme for dyspnea-bearing patients and their caregivers

Cancer-Watch

Risk of colorectal and breast cancer with widespread drinking water chemical contaminants

EUthyroid

Towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe

EGG/EAGLE

Early Genetics Growth/Early Genetics and Lifecourse Epidemiology

APACHE

Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe

ECHOCAT

Urban environment and childhood obesity in Catalonia

ENDOLUNG

Endocrine Disruptors and Childhood Lung Function and Asthma

LIFECYCLE

Early-life stressors and LifeCycle health

WALNUTS

Long-chain Polyunsaturated Fatty Acids and Adolescent Brain Development: A Dietary Intervention

INMA Cardio

Exposiciones ambientales a edad temprana y riesgo cardiovascular del adolescente

OMEGA-BRAIN

ÁCIDOS GRASOS, POLUCIÓN ATMOSFÉRICA Y DESARROLLO NEUROPSICOLÓGICO

ATHLETE

Advancing Tools for Human Early Lifecourse Exposome Research and Translation

MOOD-COVID

Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic