Entorno Urbano y Salud Cardiometabólica desde el Nacimiento hasta la Adolescencia

UrbaMet project
Photo: Claire Zhu / Unsplash
01/05/2019 - 30/04/2021
Martine Vrijheid
Funded by
Instituto de Salud Carlos III

The understanding of how the urban environments affect health has been recognized as an urgent research priority. Urban environments are complex systems and there is a need to better understand how different domains of the urban environment interact with different individual behaviours and with a wide range of cardio-metabolic health outcomes during childhood.


UrbaMet aims to examine whether exposures in the urban environment influence cardio-metabolic health trajectories in children up to age 15 years in the longitudinal birth cohort study INMA, using state-of-the-art geographic information systems (GIS), biomarker, sensor, and imaging approaches to accurately assess exposures, outcomes, and mediators.

UrbaMet will start a new follow-up examination of the INMA children at 14-15 years of age (500 participants). As part of UrbaMet we will measure cardio-metabolic outcomes (pulse wave velocity, carotid intima media thickness, blood pressure, body mass index, body fat mass and distribution, lipid profiles, liver enzymes, and insulin resistance) in the children.

Urban environment measures (for the built environment, walkability, green spaces, food environment, and social environment) will be linked to geocodes using GIS. Data on mediating behaviours such as physical activity, sleep, diet, and commuting mode will be collected from the adolescents using novel sensors and computerised questionnaire tools. Stress levels will be measured through cortisol in hair.

UrbaMet is novel in that it will be the first longitudinal study to combine measurements of multiple urban environment domains during sensitive developmental time periods (early-life) with a comprehensive and longitudinal assessment of cardio-metabolic health and behavioural risk factors up until adolescence.

Total Funding

75,020 €

Our Team


  • Martine Vrijheid
    Martine Vrijheid Head of the Childhood and Environment Programme, Research Professor and Coordinator of INMA-Sabadell Cohort

ISGlobal Team

Other projects

See Past Projects


Early Genetics Growth/Early Genetics and Lifecourse Epidemiology


Pregnancy and Childhood Epigenetics


Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe


Early-life stressors and LifeCycle health


Advancing Tools for Human Early Lifecourse Exposome Research and Translation


Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic


A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health


An integrative strategy of testing systems for identification of EDs related to metabolic disorders

The Lungfit Project

Socioeconomic Status, Physical Activity, and Respiratory Health in Pregnant Women, Children, and Adolescents


Prenatal Exposure to Environmental Pollutants and Metabolic and Cardiovascular Health of the Teenagers


Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics


Developmental origins of child liver injury: the effect of early life environmental exposures


Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways


Exposures to light pollution and heat, and neurodevelopment in adolescents


Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility


Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development


Traffic-Related Air Pollution and Birth Weight: the Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status

The APBO Project

Air Pollution and Birth Outcomes: Windows of Exposure and Health and Economic Impact Assessment


Radio Frequency Electromagnetic Fields, Noise, and Sleep Disorders in Adolescence


Prenatal Exposure to a Family of Short Half-Life Endocrine Disruptors, Dysregulation of the Hypothalamic–Pituitary–Adrenal Axis and Potential Implication for Child Neurodevelopment at Early Age


Caractérisation des usages et de l’exposition aux radiofréquences induite par les dispositifs de communication mobiles chez les enfants


Light at Night Exposure and Sleep Quality


Radiofrequency Electromagnetic Fields, Other Environmental Factors, and Development of the Embryo and Fetus


The Impact of Maternal-Fetal Steroid Metabolome Exposure on Child GROwth and Neurological Outcomes


The role of seafood and nut consumption on human neurodevelopment from pregnancy to adolescence


Air Pollution, Gut Microbiota and Neurodevelopment in the First 24 Months of Life


Urban and social environment and childhood obesity – a natural moving2health experiment