Research Programmes
Antimicrobial Resistance

Novel Marine Biomolecules against Biofilm (NoMorFilm)

Application to medical devices

Duration
01/04/2015 - 31/12/2019
Coordinator
Sara Soto
Funded by
Horizon 2020 (European Commission)
Website
http://www.nomorfilm.eu

Over 800,000 prostheses, and an even higher number of catheters, are inserted in patients in the European Union every year. Out of these patients, 7.5% suffer from a post-implant infection. A new surgical intervention to replace the implant is then required with a cost that oscillates between 30,000 and 50,000 euros per patient, depending on the country.

The bacteria and fungi found in infected prostheses do not respond to conventional antibiotics because these pathogens proliferate on the surfaces of the prostheses, or on the inside of the catheters, forming a microbial film called biofilm for which there is no pharmacological treatment. Hence, the search for new effective antibiotics that prevent the formation of biofilm and the resulting replacement of prostheses is of vital importance.

NoMorFilm is a project focused on the search for new biomolecules based on microalgae with antibiotic and antibiofilm activity, which could be incorporated into the prostheses or catheters during the manufacturing process, and thus avoid the complications that can arise after they have been inserted into the patient.

Our Team

Our Team

  • Sara Soto
    Sara Soto Associate Research Professor and Head of the Viral and Bacterial Infections Programme at ISGlobal.

Other projects

See Past Projects

COMBACTE

Combating Bacterial Resistance In Europe

COMBACTE-CARE

Combatting Bacterial Resistance in Europe - Carbapenem Resistance

Xpatial-TB

Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique

WHIP3TB

Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals

VINCI

Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique

INTE-AFRICA

Integrating and decentralizing diabetes and hypertension services in Africa

AVATAR

Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.

COVID-PREG

Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo

AMR DetecTool

A breakthrough device for the rapid detection of antimicrobial resistance

ANTICOV

Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19

HBV-COMSAVA

Hepatitis B Virus COMmunity Screening and Vaccination in Africans

Stool4TB

Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV

Hep C Free Baleares

Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.

CAPTB

Close the Gap, Increase Access, Provide Adequate Therapy

STREESCO

Strengthening Epidemiological Surveillance in Benin and Burkina Faso for an Effective Response to COVID-19

COVAIR-CAT

Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia

TB-RECONNECT

Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status

SToolNIH

Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring