- 01/04/2015 - 31/12/2019
- Sara Soto
- Funded by
- Horizon 2020 (European Commission)
Over 800,000 prostheses, and an even higher number of catheters, are inserted in patients in the European Union every year. Out of these patients, 7.5% suffer from a post-implant infection. A new surgical intervention to replace the implant is then required with a cost that oscillates between 30,000 and 50,000 euros per patient, depending on the country.
The bacteria and fungi found in infected prostheses do not respond to conventional antibiotics because these pathogens proliferate on the surfaces of the prostheses, or on the inside of the catheters, forming a microbial film called biofilm for which there is no pharmacological treatment. Hence, the search for new effective antibiotics that prevent the formation of biofilm and the resulting replacement of prostheses is of vital importance.
NoMorFilm is a project focused on the search for new biomolecules based on microalgae with antibiotic and antibiofilm activity, which could be incorporated into the prostheses or catheters during the manufacturing process, and thus avoid the complications that can arise after they have been inserted into the patient.
Sara Soto Associate Research Professor
Other projectsSee Past Projects
Combating Bacterial Resistance In Europe
Combatting Bacterial Resistance in Europe - Carbapenem Resistancehttps://www.imi.europa.eu/content/combacte-care
Prioritising Antimicrobial Resistance: establishing an interdisciplinary International Research Partnership to tackle an evolving global health threat
An interdisciplinary International Research Partnership to tackle an evolving global health threat
Development of new metal-antibiotics against pathogens causing chronic infections in patients with cystic fibrosis.
New metal-antibiotics for patients with cystic fibrosis
Non-invasive ultrasound-based screening for meningitis: Proof-of concept in infants
Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique
Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individualshttps://clinicaltrials.gov/ct2/show/NCT02980016
Search for new target proteins and use of antibacterial or inhibitory peptides against resistance mechanisms in 'Acinetobacter baumannii'
Development of New Metalloantibiotics Against Pathogens Associated to Chronic Infections in Cystic Fibrosis Patients
Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique
Integrating and decentralizing diabetes and hypertension services in Africahttp://inteafrica.org/
Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.