- 01/04/2015 - 31/12/2019
- Sara Soto
- Funded by
- Horizon 2020 (European Commission)
Over 800,000 prostheses, and an even higher number of catheters, are inserted in patients in the European Union every year. Out of these patients, 7.5% suffer from a post-implant infection. A new surgical intervention to replace the implant is then required with a cost that oscillates between 30,000 and 50,000 euros per patient, depending on the country.
The bacteria and fungi found in infected prostheses do not respond to conventional antibiotics because these pathogens proliferate on the surfaces of the prostheses, or on the inside of the catheters, forming a microbial film called biofilm for which there is no pharmacological treatment. Hence, the search for new effective antibiotics that prevent the formation of biofilm and the resulting replacement of prostheses is of vital importance.
NoMorFilm is a project focused on the search for new biomolecules based on microalgae with antibiotic and antibiofilm activity, which could be incorporated into the prostheses or catheters during the manufacturing process, and thus avoid the complications that can arise after they have been inserted into the patient.
- Sara Soto Associate Research Professor and Head of the Viral and Bacterial Infections Programme at ISGlobal.
Other projectsSee Past Projects
Combating Bacterial Resistance In Europe
Combatting Bacterial Resistance in Europe - Carbapenem Resistance
Prioritising Antimicrobial Resistance: establishing an interdisciplinary International Research Partnership to tackle an evolving global health threat
An interdisciplinary International Research Partnership to tackle an evolving global health threat
Development of new metal-antibiotics against pathogens causing chronic infections in patients with cystic fibrosis.
New metal-antibiotics for patients with cystic fibrosis
Non-invasive ultrasound-based screening for meningitis: Proof-of concept in infants
Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique
Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals
Search for new target proteins and use of antibacterial or inhibitory peptides against resistance mechanisms in 'Acinetobacter baumannii'
Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique
Integrating and decentralizing diabetes and hypertension services in Africa
Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.
Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo
Pilot Study to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission
Cendea de Cizur
Conèixer la propagació. Entendre la protecció
A breakthrough device for the rapid detection of antimicrobial resistance
Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19
Hepatitis B Virus COMmunity Screening and Vaccination in Africans
Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV
Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.
Close the Gap, Increase Access, Provide Adequate Therapy
Strengthening Epidemiological Surveillance in Benin and Burkina Faso for an Effective Response to COVID-19
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia
Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status
Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring