This programme aims to expand our current scientific understanding of the most relevant and neglected diseases affecting humans, and their host-vector interactions, in order to support evidence-based policy-making for the control and eventual elimination of these diseases.
We focus on malaria and neglected parasitic diseases such as Chagas, Dengue, soil transmitted helminths and leishmaniasis.
We apply methods which include basic cell and molecular biology, omics, immunology, epidemiology, intervention trials with drugs, vaccines and diagnostic tools, surveillance and implementation science.
Main Research Areas
This program has international leadership in:
- Basic science for a better understanding of the biology and host-pathogen interactions of these diseases.
- Development and evaluation of new tools /strategies for the treatment and control of these diseases.
- Surveillance and implementation science.
Capacity building is included at all levels.
This multidisciplinary research program addresses malaria and neglected parasitic diseases through a robust and integrated framework spanning biology of host-parasite interactions and the molecular basis of physiopathology, immunological mechanisms and vaccine development, epidemiological research, public and migrant health, clinical interventions, diagnostics and prevention tools, and implementation science, surveillance, and economics. Currently, the program includes 26 Principal Investigators (PIs) primarily affiliated with it, along with additional PIs affiliated with other programs who share several research lines. The program relies firmly in our original partnerships with Mozambique, Marruecos, and Bolivia, the latter now extended to Paraguay. In addition, actively pursuing strategic alliances with institutions in endemic regions, including other countries in sub-Saharan Africa, Sierra Leone and Togo, countries with P. vivax (Brazil, Colombia, Ethiopia, Cambodia) and Leishmania (Tunisia). Worth of mentioning, recent International collaboration efforts: (i) online meetings are being held with scientists from FIOCRUZ, and (ii) in-person meetings with researchers from ISGlobal and PTI–Salud Global CSIC to explore funding opportunities for cross-cutting programs. (iii) NHEPACHA (Nuevas Herramientas para Pacientes con Chagas).
Research Groups
- Chagas Disease and other Emergent and Re-Emergent Diseases (Julio Alonso Padilla, Quim Gascon)
- Global Health Economics (Elisa Sicuri)
- Malaria Epidemiology, Operational Research and Implementation Science (Caterina Guinovart)
- Malaria Epigenetics (Alfred Cortés)
- Malaria Immunology (Carlota Dobaño, Gemma Moncunill)
- Malaria Physiopathology and Genomics (Alfredo Mayor)
- Migrant Health (Ana Requena)
- Nanoparticles and Malaria (Xavier Fernández Busquets)
- Glycobiology and Malaria Parasite Biology (Luis Izquierdo)
- PvREX - Plasmodium vivax and Exosome (Hernando A. del Portillo, Carmen Fernández Becerra)
Strategic Alliances in Endemic Regions
Related Impact Stories
Path to Zero: Guiding malaria elimination efforts in Mozambique and beyond
Unveiling the Culprits: A new method to identify causes of death in low-income countries
Our Team
Leadership
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Hernando del Portillo Obando ICREA Research Professor and Head of the Malaria and Neglected Parasitic Diseases Programme
Principal lnvestigators of the Programme
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Ana Requena Méndez Associate Research Professor
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Quique Bassat Orellana Director General
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Julio Alonso Padilla Senior Research Leader, Director of the Chagas Initiative
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Alba Maria Antequera Associated Researcher
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Cristina Ballart Associated Researcher
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Azucena Bardají Associate Research Professor
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Bàrbara Baro Assistant Research Professor
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Daniel Camprubí Assistant Research Professor
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Alfred Cortés ICREA Research Professor
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Carlota Dobaño Research Professor
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Carmen Fernández Associate Research Professor
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XAVIER FERNANDEZ BUSQUETS
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Montserrat Gállego Associated Researcher
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Quim Gascon Research Professor
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Caterina Guinovart Senior Advisor for Research and Implementation on malaria elimination
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Luis Izquierdo Lázaro Associate Research Professor
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Alfredo Mayor Research Professor
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Clara Menéndez Research Professor, Director of the Maternal, Child and Reproductive Health Initiative and Programme
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Gemma Moncunill Senior Research Leader
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Jose Muñoz Associate Research Professor
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Krijn Paaijmans Associated Researcher
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Claudio Parolo Associated Researcher
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Regina Rabinovich Director of the Malaria Elimination Initiative
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Davide Rasella ICREA Research Professor and Head of the Health Impact Assessment and Evaluation Group
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Natalia Rodríguez-Valero Associated Researcher
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Elisa Sicuri Associate Research Professor