Malaria
Approximately half of the world population lives at risk of malaria
According to the 2017 World Malaria Report, 91 countires confirmed almost 216 million cases in 2016 (an increase of 5 million compared to the previous year).
In 2016, malaria killed more than 445,000 people. Fifteen countries accounted for 80% of global deaths; all of them except one are in Subsaharan Africa, where 9 out of 10 deaths occurred.
Main Lines of Research
- Enabling technologies for malaria research
- Parasite biology
- Pathophysiology
- Malaria immunology
- Diagnostics
- Evaluation of preventive and therapeutic tools
- Epidemiology and clinical presentation of Plasmodium falciparum and Plasmodium vivax
- Vector biology and control
- Novel approaches and strategies for malaria elimination
- Health economy studies and assessment of the economic impact of malaria elimination
Highlighted Projects
MESA
The Malaria Eradication Scientific Alliance - MESA is dedicated to advancing the science of malaria eradication.
http://www.malariaeradication.org/
RTS,S Vaccine Immunology Study
Study of immune correlates of protection against malaria after vaccination with RTS,S/AS01E: a comprehensive immunological arm of a Phase III double-blind, randomized, controlled multi-center trial
http://www.sysmalvac.eu/
Mozambican Alliance Towards Elimination of Malaria (MALTEM)
Mozambican Alliance Towards Elimination of Malaria
MiPMon
Pregnant women as a sentinel group for malaria surveillance in an era of changing malaria transmission
Other projects
See Past ProjectsPreventing infectious bites: Repulsing mosquito vectors with electric field pulsations
PlasmoSugars
Exploration of the singularities of the sugar nucleotide metabolism and description of novel glycosylation pathways in the malaria parasite
GlycoPar
Parasite glycobiology and anti-parasitic strategies
http://www.glycopar.eu/Function and mechanism of O-fucosylation of malaria TSR-domain proteins
Function and mechanism of O-fucolsylation of malaria TSR-domain proteins
AlphaGal
Exploration of the singularities of the sugar nucleotide metabolism and description of novel glycosylation pathways in the malaria parasite
Epigenetic variation in malaria parasites II
Investigating new aspects of the mechanisms and biological functions of epigenetic variation in malaria parasites
Exosomes for neglected diseases
Exosomes: new intercellular communicators and their applicability as therapeutic agents in neglected parasitic diseases
Mechanistic aspects of P. vivax
Mechanistic aspects of anemia and splenomegaly caused by plasmodium vivax, a neglected human parasite
http://www.pvrex.com/REDIEX
Network of excellence in research and innovation in exosomas
http://rediex.org/NANOpheles
Development of nanovectors for the targeted delivery in Anopheles mosquitoes of agents blocking transmission of Plasmodium parasites