- 01/05/2022 - 30/04/2025
- Ibrahim Abubakhar (University College of London - UCL)
- Funded by
- European Commission, Horizon 2021-2024
The END-VOC consortium will support the European and global response to the COVID-19 pandemic and Variants of Concern (VOC) through well-characterised cohorts and linked with existing European and international initiatives.
END-VOC consists of 19 partners in Europe (UK, Spain, Italy, Germany, Netherlands, Norway, Italy), South America (Brazil and Peru), Africa (Mozambique, South Africa, Nigeria and 13 ANTICOV African countries), Middle East (Palestine) and Asia (India, Pakistan, Philippines) with a focus on countries affected by VOCs and VOIs.
The project aims to elucidate the global circulation of the current and emerging SARS-CoV-2 VOCs and their characteristics, including transmissibility, pathogenicity and propensity to cause reinfection, to support best control strategies and the development of diagnostics; evaluate the impact of VOCs on the effectiveness of different vaccines and vaccination strategies, and assess the implications of VOCs on the choice of optimal treatment options.
END-VOC will also investigate how VOCs alter long-term post-infection sequelae and where new VOCs emerge within hosts using our clinical cohorts.
The project will inform future preparedness and response by working closely with international and national public health organisations and existing cohort consortia. Specific beyond state-of-the-art components of END-VOC include the use of novel phylogenetic prediction tools and mathematical modelling; generation of powerful cohorts through sentinel surveillance in low and middle-income settings and cohorts of travellers to increase our global reach; use of novel predictive modelling of clinical outcomes by VOC and comorbidity/treatment and evaluation of differences in natural and vaccine immunity by VOC; antiviral screening models within cohorts and artificial intelligence-driven tool for the prediction of long COVID.
Elisabet Cardis Research Professor, Head of the Radiation Group
Quique Bassat Director General
Gemma Castaño Staff Scientist
PATRICIA DE LLOBET Research technician
Elizabet Diago Associated Researcher
Carlota Dobaño Research Professor
Gonzalo Fanjul Policy Director
Other projectsSee Past Projects
Combating Bacterial Resistance In Europe
Development of Novel Gastrointestinal Biomarkers for Use in HIV Incidence Determination in a Sub-Saharan African Setting
Application to medical devices
Combatting Bacterial Resistance in Europe - Carbapenem Resistance
Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women
Integrating and decentralizing diabetes and hypertension services in Africa
Improving Care through Azithromycin Research for Infants in Africa
Predicting the Future: Incipient Tuberculosis
Cendea de Cizur
Conèixer la propagació. Entendre la protecció
Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19
Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV
Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status
Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring
Planificación urbana, medio ambiente y salud | Clima y salud | Resistencias Antimicrobianas
Digital Twins Enabled Indoor Air Quality Management for Healthy Living
Estudio de la propagación de bacterias y genes de resistencia a los antibióticos en el ciclo integral del agua, en el área metropolitana de Barcelona
Propagación de la resistencia en aguas
Project Code: DTS21/00004
Más allá de la supresión vírica del VIH: un cuarto noventa para mejorar la salud de personas viviendo con el VIH en España
Project Code: PI20/01654
Community knowledge generation through scientific culture, urban ecology and art
Building Scalable Pathogen Genomic Epidemiology in Ethiopia
Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.
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