Equip ISGlobal - Títol

Equip ISGlobal

Julio Alonso Padilla

Julio Alonso Padilla

Assistant Research Professor, Director of the Chagas Initiative Chagas, Chagas

Julio Alonso Padilla graduated in Biology in the Universidad Autónoma de Madrid, and obtained a PhD in Molecular Biology in the same university in 2010.

He worked for several years with viruses of veterinary and medical relevance before switching subjects to Parasitology.

At present he is responsible for the laboratory of Trypanosoma cruzi biology at ISGlobal. This protozoan parasite causes Chagas disease, a neglected zoonosis that affects millions of people worldwide, the majority of them in Latin America.

The main research lines of the lab include the identification of new therapeutic interventions against T. cruzi infection, and the implementation of more practical diagnostics.

Línies de recerca

  •  New therapeutic interventions for Chagas disease.
  •  Implementation of more practical diagnostic algorithms in highly endemic areas with low resources.

Publicacions principals

  • Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity. Martinez-Peinado N, Cortes-Serra N, Torras-Claveria L, Pinazo MJ, Gascon J, Bastida J, Alonso-Padilla J. Parasit Vectors. 2020 Jun 10;13(1):299. doi: 10.1186/s13071-020-04171-6.
  • Use of rapid diagnostic tests (RDTs) for conclusive diagnosis of chronic Chagas disease - field implementation in the Bolivian Chaco region. Lozano D, Rojas L, Méndez S, Casellas A, Sanz S, Ortiz L, Pinazo MJ, Abril M, Gascón J, Torrico F, Alonso-Padilla J. PLoS Negl Trop Dis. 2019 Dec 19;13(12):e0007877. doi: 10.1371/journal.pntd.0007877.
  • In silico design of an epitope-based vaccine ensemble for Chagas disease. Michel-Todó L, Reche PA, Bigey P, Pinazo MJ, Gascón J, Alonso-Padilla J. Front Immunol. 2019 Nov 22;10:2698. doi: 10.3389/fimmu.2019.02698.
  • Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America. Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Expert Rev Anti Infect Ther. 2019 Mar;17(3):145-157. doi: 10.1080/14787210.2019.1577731.
  • Molecular diagnostics for Chagas disease: up to date and novel methodologies. Alonso-Padilla J, Gallego M, Schijman AG, Gascon J. Expert Rev Mol Diagn. 2017 Jul;17(7):699-710. doi: 10.1080/14737159.2017.1338566.
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