- 01/09/2009 - 31/05/2016
- Judith Garcia Aymerich
- Funded by
- Innovative Medicines Initiative (IMI) Partner
Physical activity (PA) is essential in maintaining optimal health in chronic diseases, including COPD. More physically active COPD patients have less hospital admissions and better survival. Validated physical activity monitors have become available in recent years, but it is unknown how patients experience physical activity and how physical activity is best assessed comprehensively in patients with COPD (and chronic disease in general).
The aim of PROactive was to develop and validate two Patient Reported Outcome (PRO) instruments for the measure of physical activity in COPD patients, one for the measure on a daily basis, and the second for its use during clinical trial visits (7-days recall).
For the development of the first draft of the PROs we combined data from systematic reviews of the literature, interviews with patients, and experts’ opinion. The PROs were used in an observational longitudinal study to reduce their items and be initially validated with respect to reliability and construct validity. The resulting pre-final PROs versions were included in large multicentre clinical trials for final validation mainly with respect to validity and responsiveness to change.
The PROactive project delivered two hybrid tools combining a short PRO questionnaire and two activity monitor variables and covering two domains: difficulty with physical activities, and amount of physical activity. These tools allow the assessment of physical activity in COPD patients in a daily basis (D-PACC) or during a clinical visit (C-PACC).
Other projectsSee Past Projects
Population based multicasecontrol study on common tumours in Spain
Ageing Lungs in European Cohorts
Network on the Coordination and Harmonisation of European Occupational Cohorts
Impact Of Pollution on Asthma and Rhinitis
Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors
Leveraging the European Genome-Phenome Archive (EGA) for Industry and Society
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
Cohorte Covid-19 en Cataluña
Signs of Early Adaptation to Climate Change
Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing
Las Voces de los Afectados por la Nefropatía Mesoamericana
Co-created educational programme for dyspnea-bearing patients and their caregivers
Risk of colorectal and breast cancer with widespread drinking water chemical contaminants
Cohort of COVID-19 in Spain: social dynamics, mental health and inequalities
EXposome Powered tools for healthy living in urbAN SEttings
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia