- Manolis Kogevinas
- Funded by
- CIBERESP, FIS
The MCC-Spain study, conducted within the Spanish Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), is a unique initiative to evaluate etiological factors for common cancers and will promote cancer research and prevention in Spain.
In 2008, the CIBERESP, within the framework of Cross-Sectional Action in Cancer, provided the resources to launch a population-based multicase-control study (MCC-SPAIN) in order to research the influence of environmental factors and their interaction with genetic factors in frequent tumours or tumours with peculiar epidemiological characteristics in our country, in which the environmental factors involved are not sufficiently understood.
The selected tumours are colorectal cancer, breast cancer, gastroesophageal cancer and prostate cancer. Chronic lymphocytic leukaemia (CLL) has been recently added to the study. Colorectal cancer has been selected due to its frequency in both sexes. Gastroesophageal cancer has been selected due to its characteristic geographic pattern and the environmental hypotheses suggested. Prostate cancer has been chosen due to its frequency and its hormonal nature, sharing with breast cancer the etiological hypotheses of endocrine disruption. The study involves data collection using an interview as well as the obtention of several biological samples. The population controls have been selected from primary care centre lists and interviews are performed in these centres.
The MCC-Spain study is coordinated by Manolis Kogevinas (ISGlobal) and Marina Pollan (ISCIII). Researchers from the CIBERESP in 11 autonomous communities of Spain (Catalonia, Madrid, Asturias, Navarra, Basque Country, Murcia, Cantabria, Andalusia, Valencia, Castilla y Leon) are participating in the study. Up until March 2010 information and biologic samples were obtained from 1,600 population controls, 1,200 colon and rectum cases, 750 breast cancer cases, 450 prostate cancer cases, 120 stomach cancer cases, and the collection of leukaemia cases was initiated.
Principal Investigator (PI)
- Emmanouil Kogevinas
- Maria Cecilia Persavento
- Marius Joannes Nieuwenhuijsen
- Mariona Bustamante Staff Scientist
- Cristina Villanueva Associate Research Professor
- Lourdes Arjona Research Technician
- Gemma Castaño Project Manager
Other projectsSee Past Projects
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Network on the Coordination and Harmonisation of European Occupational Cohorts
Impact Of Pollution on Asthma and Rhinitis
Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors
Leveraging the European Genome-Phenome Archive (EGA) for Industry and Society
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
Cohorte Covid-19 en Cataluña
Signs of Early Adaptation to Climate Change
Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing
Las Voces de los Afectados por la Nefropatía Mesoamericana
Co-created educational programme for dyspnea-bearing patients and their caregivers
Risk of colorectal and breast cancer with widespread drinking water chemical contaminants
Cohort of COVID-19 in Spain: social dynamics, mental health and inequalities
EXposome Powered tools for healthy living in urbAN SEttings
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia