Research, Maternal, Child and Reproductive Health

MA-CoV

Prevalence and impact of SARS-CoV-2 infection on maternal and infant health in African populations

Duration
2021-2023
Coordinator
Raquel González (ISGlobal)
Funded by
EDCTP (Project code: RIA2020EF-2956)

The highest maternal mortality rates in the world are registered in sub-Saharan Africa (SSA), were the number of confirmed COVID-19 cases reported continues to increase. Information on SARS-CoV-2 and associated COVID-19 in pregnancy and their effects on maternal and perinatal health remains limited mainly to high-income countries. Thus, there is a paucity of data from SSA, where there is coexisting and highly prevalent HIV, malaria and malnutrition, and some of the poorest maternal and child health outcomes globally.

There is an urgent need to conduct surveillance and prospective studies across the region. This project aims to describe the burden and effects of SARS-CoV-2 infection during pregnancy in women living in malaria endemic areas and high prevalence of HIV infection. Pregnant women attending ANC clinics in selected sites from Libreville and Lambaréné (Gabon) and Manhiça (Mozambique) will be enrolled in a cohort study to determine the frequency of SARS-CoV-2 infection and COVID-19 during pregnancy and its effects on maternal and neonatal health.

The findings of this project will contribute to the understanding of the impact of SARS-CoV-2 and COVID-19 among pregnant women living in SSA countries where malaria and HIV infections are highly prevalent.

Budget

499,999 euros

 

Our Team

Principal Investigator (PI)

ISGlobal Team

See More

Other projects

See Past Projects

MAMAH

Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women

CaDMIA-plus

Continued validation of the minimally invasive autopsy for the investigation of the causes of death in infants, and establishment of a research and training center to study causes of death

TIPTOP

Transforming IPT for optimal pregnancy

METRO

Measuring community prevalence among HIV exposed children in rural Southern Mozambique

ICARIA

Improving Care through Azithromycin Research for Infants in Africa

MIBio

Identification of Prematurity and Pre-Eclampsia as Causes of Mortality

STREESCO

Strengthening Epidemiological Surveillance in Benin and Burkina Faso for an Effective Response to COVID-19

MULTIPLY

MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention