Publicador de contenidos

REDIEX

Network of excellence in research and innovation in exosomas

Duración
20/11/2015-30/11/2017
Coordinador
Hernando A. del Portillo
Financiadores
MINECO
Página web
http://rediex.org/

Research on exosomes is increasingly appreciated in the clinical setting and it is likely that it will impact even more in the future. Exosomes have been found to carry selective biomarkers of disease, playing an essential role in the transfer of information and molecules between different cells involved in the regulation of several physiological and pathological processes.

This Network of Excellence for Research and Innovation on Exosomes (REDiEX) will focus its activity on strengthening the interaction between different Spanish groups that study this type of vesicles. REDiEX will integrate the experience and know-how of the different groups with a clear and innovative vision that will boost translational applications of vesicle analyses in human health. 

REDiEX will promote online and face-to-face scientific meetings, the mobility of personnel between the different laboratories and the optimization and attraction of resources to study several aspects of vesicle biology:

1) the development of new methodologies for the study of exosomes in animal models and patient samples;

2) the identification of non-invasive biomarkers;

3) search for novel therapeutic targets;

4) the analysis of intercellular communication processes mediated by exosomes in models of both development and cancer for the prediction of metastatic niches;

5) the role of exosomes as biomarkers and immune mediators and as a tool for diagnosis;

6) the development of vaccines against rare parasitic diseases.

Our overall objective is to develop and standardize methodologies, accelerating the identification and development of non-invasive biomarkers as well as define new strategies to tackle major diseases such as cancer and parasitic diseases.

Thus, REDiEX signifies a significant advance towards personalized medicine aiming to develop new tools and markers with high social impact that will generate economic benefits and equity in global health.

Total funding

46,000 €

 

Nuestro equipo

Principal Investigator

  • Hernando Del Portillo Obando
    Hernando Del Portillo Obando

ISGlobal Team

Otros proyectos

GlycoTargets

Nuevas terapias antimaláricas dirigidas contra las vías de glicosilación de 'Plasmodium falciparum'

CLIMSOCTRYPBOL

Insight on climate and social participatory research for integral management of vectorborne zoonosis caused by Trypanosoma cruzi and Leishmania spp. in the Bolivian Gran Chaco.

VaMonoS

Unravelling the heterogoneity and function of monocytes in vaccination and immunity to malaria

VivaxEVTalk

Extracellular Vesicles as Intercellular Communicators and Biomarkers of Cryptic Erythrocytic Infections in Plasmodium vivax malaria

RESPONSE

Mechanisms of the transcriptional responses to changes in the environment in the malaria parasite Plasmodium falciparum

MalTransc

Transcriptional regulation of adaptation and developmental decisions in malaria parasites: from epigenetic variation to directed transcriptional responses

SMART

Identifying Severe Malaria with a new Aptamer-based Rapid diagnostic Test

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia