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Research

SToolNIH

Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring

Unidad de desnutrición infantil en la planta de Pediatría del Hospital de Manhiça
Duration
01/09/2020 - 01/09/2024
Coordinator
Anna Maria Mandalakas / Alberto García-Basteiro
Funded by
National Institutes of Health (NIH)

This project aims to validate an innovative stool homogenization and DNA isolation method that yields a highly sensitive and specific Mtb qPCR-based diagnostic. StoolTB will evaluate this platform in the high TB and HIV burden settings of Mozambique, eSwatini and Uganda under the hypothesis that it will narrow the large TB case detection gap by improving TB confirmation rates in children and people living with HIV while proving feasible and acceptable.

Total Funding

$ 2,475,880.00

Our Team

Coordinators

  • Alberto García Basteiro
    Alberto García Basteiro
  • Anna Maria Mandalakas
    Anna Maria Mandalakas

ISGlobal Team

  • Lucía Carratalá
    Lucía Carratalá Medical Research Fellow
  • Elisa Blanca López Varela
    Elisa Blanca López Varela
  • Belén Saavedra Cervera
    Belén Saavedra Cervera