Duration
2012-2016
Coordinator
Paolo Vineis (Imperial College, London)
Funded by
European Comission
This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero.

Although environmental (i.e. non-genetic) exposures account for the majority of diseases currently there is no standard or systematic way to measure the influence of environmental exposures on health. This project will move the field forward by developing a personal exposure monitoring (PEM) system (including sensors, smartphones, geo-referencing, satellites) and collect data on individual external exposome as well as analysing biological samples (internal markers of external exposures) using multiple “omic” technologies. The search for the relationships between external exposures (as measured by PEM, which has not previously been used in large scale studies) and global profiles of molecular features (as measured by omics) in the same individuals constitutes a novel advance towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as ‘exposome-wide association studies’ (EWAS).

The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease.

Our Team

Principal Investigator (PI)

  • alt text
    Mark Nieuwenhuijsen Director of the Urban Planning, Environment and Health Initiative, and head of the Air Pollution and Urban Environment Programme

Our Team

See More

Other projects

See Past Projects

ESCAPE

European Study of Cohorts for Air Pollution Effects

ESAIRE

Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality

http://www.esaire.eu

EARLY COPD

Onset and progression determinants of COPD in young adults

EGG/EAGLE

Early Genetics Growth/Early Genetics and Lifecourse Epidemiology

APACHE

Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe

ECHOCAT

Urban environment and childhood obesity in Catalonia

WALNUTS

Long-chain Polyunsaturated Fatty Acids and Adolescent Brain Development: A Dietary Intervention

INMA Cardio

Exposiciones ambientales a edad temprana y riesgo cardiovascular del adolescente

OMEGA-BRAIN

ÁCIDOS GRASOS, POLUCIÓN ATMOSFÉRICA Y DESARROLLO NEUROPSICOLÓGICO