Antimicrobial Resistance


Combating Bacterial Resistance In Europe

The concept of the COMBACTE project is to develop a broad European network of fully capable and Good Clinical Practice (GCP) compliant clinical investigation sites to execute clinical trials enabling the registration of novel agents to be used in the treatment of patients with resistant bacterial infections. The growth and application of the network will be supported with robust microbiologic surveillance data and clinical epidemiologic data. To reduce the time and or cost of clinical development, novel clinical trial designs will be outlined and supported through analysis of publically available and consortium-shared non-clinical and clinical data. In addition to executing the initial set of clinical trials, investigations of patient and pathogen-related biomarkers and the logistical and decision making impact of rapid diagnostics will be conducted.

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Other projects

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Combatting Bacterial Resistance in Europe - Carbapenem Resistance


Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique


Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals


Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique


Integrating and decentralizing diabetes and hypertension services in Africa


Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.


Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo