Recerca - El nostre equip

Juan R. González is a Research Professor at ISGlobal, where he coordinates the Health Analytics Hub (and SGR group). With over 220 peer-reviewed publications and an H-index of 54, he is internationally recognized for his contributions to bioinformatics and genetic epidemiology. His work stands out for its strong translational dimension, driving the application of multi-omics analytics and artificial intelligence to cancer, fertility, and neurodegenerative diseases such as Alzheimer’s.

A pioneer in developing widely used tools such as SNPassoc and several DataSHIELD packages, he has enabled secure and reproducible analysis of sensitive biomedical data at scale. He is also an Adjunct Professor at the Autonomous University of Barcelona and author of the reference textbook Omic Association Studies with R and Bioconductor (CRC Press), shaping the next generation of health data scientists.

Beyond academia, Juan R. González actively bridges research and industry. He has contributed to innovation pipelines through collaborations with companies such as qGEnomics, TruDiagnostic, Made of Genes, and Onalabs, delivering actionable solutions in biological aging, precision medicine, and sportomics. He embodies the intersection of statistical rigor, computational innovation, and real-world health impact, advancing data-driven prevention and personalized therapies in global health.

Línies de recerca

• Health Data Science, Statistical Methodology & Open-tools
• Genetic and Epigenetic Epidemiology
• Translational Applications in Cancer, Fertility, and Alzheimer’s Disease
• Secure Federated Analytics
• Biological Aging and Digital Biomarkers
• Exposome Analytics

Publicacions principals

• Sarrat-González D, Escribà-Montagut X, Houghtaling J, González JR. dsOMOP: bridging OMOP CDM and DataSHIELD for secure federated analysis of standardized clinical data. Bioinformatics. 2025 Jun 2;41(6):btaf286. doi: 10.1093/bioinformatics/btaf286. 
• Cáceres A, Pérez-Jurado LA, Alegret-García A, Dwaraka VB, Smith R, González JR. Defective X-chromosome inactivation and cancer risk in women. Commun Biol. 2025 Feb 22;8(1):289. doi: 10.1038/s42003-025-07691-y. 
• Escriba-Montagut X, Marcon Y, Anguita-Ruiz A, Avraam D, Urquiza J, Morgan AS, Wilson RC, Burton P, Gonzalez JR. Federated privacy-protected meta- and mega-omics data analysis in multi-center studies with a fully open-source analytic platform. PLoS Comput Biol. 2024 Dec 9;20(12):e1012626. doi: 10.1371/journal.pcbi.1012626. 
• Maitre L, Bustamante M, Hernández-Ferrer C, Thiel D, Lau CE, Siskos AP, Vives-Usano M, Ruiz-Arenas C, Pelegrí-Sisó D, Robinson O, Mason D, Wright J, Cadiou S, Slama R, Heude B, Casas M, Sunyer J, Papadopoulou EZ, Gutzkow KB, Andrusaityte S, Grazuleviciene R, Vafeiadi M, Chatzi L, Sakhi AK, Thomsen C, Tamayo I, Nieuwenhuijsen M, Urquiza J, Borràs E, Sabidó E, Quintela I, Carracedo Á, Estivill X, Coen M, González JR*, Keun HC*, Vrijheid M*. Multi-omics signatures of the human early life exposome. Nat Commun. 2022 Nov 21;13(1):7024. doi: 10.1038/s41467-022-34422-2. 
• Balagué-Dobón L, Cáceres A, González JR. Fully exploiting SNP arrays: a systematic review on the tools to extract underlying genomic structure. Brief Bioinform. 2022 Mar 10;23(2):bbac043. doi: 10.1093/bib/bbac043.