Javier Gandasegui obtained a MSc and PhD degree in Health and Development in the Tropics in by the University if Salamanca. During his PhD, Javier gained a strong background in DNA detections-based diagnostic of neglected helminthiasis. Besides, he designed, evaluated and validated these methods in animal models and through field studies in endemic countries (Angola, Brazil and Mozambique). At the same time, he obtained several awards, highlighting the extraordinary PhD award of the University of Salamanca.
Afterwards, he obtained international recognised postdoctoral fellowships in competitive calls: the Ramón Areces Foundation International Fellowships, the Juan de la Cierva Fellowship, and more recently, a new Postdoctoral Fellowship at the Barcelona Institute of Global Health under the Severo Ochoa Excellence Programme, with the main aim of investigating the role of microbiome in treatment response in neglected tropical infections.
In the recent years, Javier has been focused on the study of soil-transmitted helminths infections and the emergence of anthelmintic resistance. He studied a MSc in Bioinformatics and Genetic Epidemiology at Cardiff University and is now working on application of genome-wide and metagenomic approaches in the discovery of novel markers that are predictive of the drug-resistance phenotype in helminth parasites.
Línies de recerca
- Molecular diagnostics of neglected helminthiasis
- Role of microbiome in drug response
- Genome-wide approaches to investigate treatment response in infectious diseases
- Javier Gandasegui; Berta Grau-Pujol; María Cambra-Pelleja; et al; María Martínez-Valladares. 2021. Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs. Parasite & Vectors. BMC.
- María Martínez-Valladares; Elora Valderas-García; Javier Gandasegui; et al; Francisco A. Rojo-Vázquez. 2020. Teladorsagia circumcincta beta tubulin: the presence of the E198L polymorphism on its own is associated with benzimidazole resistance. Parasites and Vectors. 13-453.
- Javier Gandasegui; Maria Martínez-Valladares; Berta Grau-Pujol; et al; José Muñoz. 2020. Role of DNA-detection–based tools for monitoring the soil-transmitted helminth treatment response in drug-efficacy trials PLoS Neglected Tropical Diseases. Impact factor. 14(2):e0007931.
- Javier Gandasegui; Pedro Fernández-Soto; Elena Dacal; et al; Antonio Muro. 2018. Field and laboratory comparative evaluation of a LAMP assay for the diagnosis of urogenital schistosomiasis in Cubal, Central Angola Tropical Medicine and International Health.
- Javier Gandasegui; Pedro Fernández-Soto; Antonio Muro; Constanca Simoes Barbosa; Fabio Lopes de Melo; Rodrigo Loyo; Elainne Christine de Souza Gomes. 2018. A field survey using LAMP assay for detection of Schistosoma mansoni in a low-transmission area of schistosomiasis in Umbuzeiro, Brazil: assessment in human and snail samples.PLOS Neglected Tropical Diseases.