Publicador de continguts

Recerca i Innovació Programes
Recerca, Planificació urbana, medi ambient i salut

CityExposomeCat

An Exposome Approach to Urban Health: Individualized Environmental Exposure Assessment in an Adults Population Cohort Study (GCAT)

Trànsit de vehicles a Barcelona i una noia en patinet pel carril bici
Foto: Laura Guerrero
Durada
01/01/2018 - 31/12/2023
Coordinador
Manolis Kogevinas
Finançadors
ISCIII, FIS PI17/01388, FEDER

The CityExposomeCat project applied an “exposome” approach to a large cohort of adults in Catalonia (CAT) to evaluate environmental exposures and lifestyle factors that are related to urban settings, and examine their association with well being and major diseases (obesity, cardiometabolic, mental health). The project eventually expanded its objectives to include COVID-19 as a major outcome (see COVICAT cohort).

Exposome approaches ultimately allow the understanding of mechanisms of disease through the use of agnostic “omic” approaches and advanced technology in environmental epidemiology.

The CityExposomeCat focuses on the evaluation of environmental (e.g. air pollution) and lifestyle factors (e.g. sleep) and their association with health, while a companion project focuses on omics.

The GCAT cohort includes around 20,000 volunteer adults in Catalonia, mostly in urban areas that have completed a first round of questionnaires, provided biological samples and who can be identified in electronic primary and secondary health registers. Residences of all subjects were geocoded and a Geographic Information System (GIS) based approach was applied to evaluate environmental exposures (proximity to natural/green spaces, urban structure, air-pollution, noise, temperature and artificial light at night) using existing information (e.g. Urban Atlas, Landsat images).

A new follow-up was conducted in 6,000 subjects recovering additional information on environmental, lifestyle and incident health related outcomes.

A validation study was conducted in a subsample (unfortunately disrupted in March 2020 due to COVID-19) using advanced technologies for individual exposure assessment (e.g. actigraphs, light measurements) that should have allowed quantification of error and calibration of exposure assessment in the whole cohort.

Total Funding

64,463 €

Related Publications

The Links Between Air Pollution and COVID-19

 

Our Team

Coordinator

ISGlobal Team

Altres projectes

AM-MENTAL

Com afecta la teva salut mental que el teu cap sigui un algoritme?

e-QuoL

e-health tools to promote Equality in Quality of Life for childhood to young adulthood cancer patients, survivors and their families

B-Triage

Una prueba en el punto de atención para la estratificación del riesgo de los pacientes febriles basada en los niveles de sTREM-1

IHEN

International Human Exposome Network

EXPONIT

Analysing and studying how night shift work affects workers' circadian rhythms and health

FINDOOR

FTIR spectroscopy for real-time detection of bacterial outbreaks and the rapid identification of pathogenic serotypes, relapsing infections and antibiotic resistance

intoDBP

Innovative Tools to Control Organic Matter and Disinfection Byproducts in Drinking Water

Veure tots els projectes relacionats