Asset Publisher

REDIEX

Network of excellence in research and innovation in exosomas

Duration
20/11/2015-30/11/2017
Coordinator
Hernando A. del Portillo
Funded by
MINECO

Research on exosomes is increasingly appreciated in the clinical setting and it is likely that it will impact even more in the future. Exosomes have been found to carry selective biomarkers of disease, playing an essential role in the transfer of information and molecules between different cells involved in the regulation of several physiological and pathological processes.

This Network of Excellence for Research and Innovation on Exosomes (REDiEX) will focus its activity on strengthening the interaction between different Spanish groups that study this type of vesicles. REDiEX will integrate the experience and know-how of the different groups with a clear and innovative vision that will boost translational applications of vesicle analyses in human health. 

REDiEX will promote online and face-to-face scientific meetings, the mobility of personnel between the different laboratories and the optimization and attraction of resources to study several aspects of vesicle biology:

1) the development of new methodologies for the study of exosomes in animal models and patient samples;

2) the identification of non-invasive biomarkers;

3) search for novel therapeutic targets;

4) the analysis of intercellular communication processes mediated by exosomes in models of both development and cancer for the prediction of metastatic niches;

5) the role of exosomes as biomarkers and immune mediators and as a tool for diagnosis;

6) the development of vaccines against rare parasitic diseases.

Our overall objective is to develop and standardize methodologies, accelerating the identification and development of non-invasive biomarkers as well as define new strategies to tackle major diseases such as cancer and parasitic diseases.

Thus, REDiEX signifies a significant advance towards personalized medicine aiming to develop new tools and markers with high social impact that will generate economic benefits and equity in global health.

Total funding

46,000 €

 

Our Team

Principal Investigator

  • Hernando Del Portillo Obando
    Hernando Del Portillo Obando

ISGlobal Team

Other projects

See Past Projects

MESA

Sharing knowledge and catalyzing research towards a malaria-free world

NHEPACHA

New Tools for the Diagnosis and Evaluation of Chagas Disease

RTS,S Vaccine Immunology Study

Study of immune correlates of protection against malaria after vaccination with RTS,S/AS01E: a comprehensive immunological arm of a Phase III double-blind, randomized, controlled multi-center trial

Euroleish.net

Control of Leishmaniasis. From bench to bedside and community

GREPIMER

Grup de recerca en patología importada i malaties emergents i re-emergents

TESEO

New chemotherapy regimens and biomarkers for Chagas Disease

ASINTMAL

Unravelling Disease Tolerance and Host Resistance in Afebrile 'P. falciparum' Infections: a Prospective Study in Mozambican Adults

ADAM

Malaria mass and focal drug administration to advance malaria elimination in Mozambique: accelerating programmatic implementation and policy translation

MULTIPLY

MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention

Science4Pandemics

Citizens engagement digital platform for collective intelligence in pandemics

HIDDENVIVAX

Novel organ-on-a-chip technology to study extracellular vesicles-mediated cryptic infections in Plasmodium vivax malaria

MENA Migrant Health

Transforming data collection and surveillance to drive migrant health research, care and policy

SexMal

Social affairs and sex in P. falciparum: implications for malaria elimination

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

SMART

Identifying Severe Malaria with a new Aptamer-based Rapid diagnostic Test

MalTransc

Transcriptional regulation of adaptation and developmental decisions in malaria parasites: from epigenetic variation to directed transcriptional responses

GenMoz

P. falciparum genomic intelligence in Mozambique

BOHEMIA

Broad One Health Endectocide-based Malaria Intervention in Africa