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Paulina Jedynak

Paulina Jedynak

Investigadora postdoctoral Salud materna, infantil y reproductiva, Infancia y medio ambiente

Paulina Jedynak is a postdoctoral researcher working on the HyPAXE project. She studies whether the level of pregnancy exposure to synthetic phenols (man-made endocrine disruptors abundantly present in the environment that may mimic or interfere with the body's hormones) can be associated to health outcomes in pregnant women and their offspring.

In 2013 Paulina obtained her PhD in molecular biology (neurosciences) and studied mechanisms behind different neurobiological disorders in rodent disease models. In 2018, she obtained a master’s degree in bioinformatics and biostatistics at the interdisciplinary unit of the UOC/UB (Barcelona, Spain) with a work on prenatal exposure to a wide range of environmental chemicals (chemical exposome) and child behaviour.

In 2019 Paulina started a post-doctoral fellowship in Rémy Slama’s team of Environmental Epidemiology applied to Development and Respiratory Health at INSERM/University Grenoble-Alpes (France). She investigated the effect of pregnancy exposure to endocrine disruptors such as phenols and phthalates on epigenetic changes in placenta, DNA methylation in particular. Paulina’s work has been the first published study investigating the associations between prenatal exposure to synthetic phenols and phthalates and placental DNA methylation on the epigenome-wide scale.

Principales publicaciones

  • Jedynak P, Tost J, Calafat AM, Bourova-Flin E, Broséus L, Busato F, et al. 2022. Pregnancy exposure to phthalates and DNA methylation in male placenta — An epigenome-wide association study. Environ Int 160:107054; doi:10.1016/j.envint.2021.107054. PMID: 35032864.
  • Jedynak P, Tost J, Calafat AM, Bourova-Flin E, Busato F, Forhan A, et al. 2021. Pregnancy exposure to synthetic phenols and placental DNA methylation - An epigenome-wide association study in male infants from the EDEN cohort. Environ Pollut 118024; doi:10.1016/j.envpol.2021.118024. PMID: 34523531.
  • Maitre L and Jedynak P, Gallego M, Ciaran L, Audouze K, Casas M, et al. 2023. Integrating -omics approaches into population-based studies of endocrine disrupting chemicals: A scoping review. Environ Res 115788; doi:10.1016/j.envres.2023.115788.
  • Jedynak P, Maitre L, Guxens M, Gützkow KB, Julvez J, López-Vicente M, et al. 2021. Prenatal exposure to a wide range of environmental chemicals and child behaviour between 3 and 7 years of age - An exposome-based approach in 5 European cohorts. Sci Total Environ 763:144115; doi:10.1016/j.scitotenv.2020.144115. PMID: 33422710.
  • Jedynak P, Rolland M, Pin I, Thomsen C, Sakhi AK, Sabaredzovic A, et al. 2022. Pregnancy Exposure to Phenols and Anthropometric Measures in Gestation and at Birth. Epidemiology 33:616–623; doi:10.1097/EDE.0000000000001515. PMID: 35700189.
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