DescripciónThe Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level. Research is organized in three main areas, Malaria and other Infectious Diseases, Child and Maternal Health, and Urban Health, Climate & Non-Communicable Diseases. ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.
What We Are Looking for
ISGlobal is seeking a postdoctoral scientist who is interested on working in the research projects of the team focused on regulation of gene expression and sexual conversion in the malaria parasite Plasmodium falciparum.
About the project
Plasmodium falciparum is responsible for the most severe forms of human malaria. Transcriptional regulation plays a key role in malaria parasite biology, as it controls fundamental processes such as life cycle progression, antigenic variation and adaptation to the conditions of the environment. Some of these processes are regulated at the epigenetic level, with a key role for euchromatin-heterochromatin transitions. Of note, the conversion of some asexual parasites into sexual forms that mediate transmission to mosquito vectors involves epigenetic processes.
We are recruiting a postdoctoral scientist to work in a project investigating heterochromatin formation in P. falciparum and its role in sexual conversion. The project will involve the use of multiple techniques including genome editing with CRISPR-Cas9 technology, transcriptomics (RNA-seq/microarrays), epigenomics (ChIP-seq) and basic molecular and cellular parasitology. Depending on the progress of the project, single-cell omics approaches may also be used.
- Biological sciences
Training and experience /Qualifications
- A PhD in a discipline related with molecular and cellular biology
- High level of enthusiasm and motivation; passion for science!
- Previous expertise in malaria research and/or in epigenetics/chromatin biology is desirable but not essential
- Bioinformatics skills are desirable but not essential
- Ability to work closely with other members of the team on a highly collaborative environment
- Experiments with P. falciparum cultures
- Molecular and cellular biology experiments
- Data analysis and preparation of manuscripts
- Present results in scientific conferences
- Contribute to scientific discussion and training of new members of the team
- Capacity to work both independently and as part of a team
- Excellent written and oral communication skills in English
- Excellent organization and coordination skills
- Demonstrated track record of achievements
- Excellent written and oral communication skills in English are essential.
- Duration: initially 12 months . There may be a possibility to extend the contract depending on availability of funds.
- Starting date: September 2021 (flexible)
- Contract: Full time
- Salary Range: According to ISGlobal salary scales, will depend on the level of experience and qualifications
How to apply
Applicants must fill in the request form and include the following code reference position: Postdoc_MalariaEpigenetics_Jun21, attach the CV and a Cover Letter. Each attached document must be named with the candidate name and surname.
The receipt of applications will be open until July 31st 2021 or until the position is covered.
Applications will be accepted until 17.00 CET of the closing date.
Only the applications submitted through the request form will be considered.
Only shortlisted candidates will be contacted.
The interviews could be placed during the reception candidatures period.