INTE-AFRICA
Integrating and decentralizing diabetes and hypertension services in Africa
- Duración
- 01/01/2019 - 31/12/2022
- Coordinador
- Liverpool School of Tropical Medicine
- Financiadores
- EU Horizon 2020
- Página web
- http://inteafrica.org/
The diseases affecting the African population have drastically changed in the last decades. Although acute infections continue to constitute a high burden, chronic diseases, which require regular lifelong care, now have an equal or higher burden.
Two of the chronic conditions of major concern are hypertension (the single largest risk factor for death, it has reached a prevalence of 20% in Africa), and diabetes (its prevalence in Africa is increasing rapidly and currently exceeds 5%).
This represents a huge challenge for Africa, where coverage of health services remains low. Less than 5% of people with diabetes or hypertension are thought to receive regular care.
INTE-Africa proposes to scale up provision for diabetes and hypertension in two countries in Africa (Uganda and Tanzania).
Objectives
The main objective of this implementation research project is to assess the effectiveness and feasibility of two approaches: scale up hypertension and diabetes integrated services alone, or in combination with HIV infection services.
The specific objectives are:
- Reorganise primary health care services so that diabetes and hypertension can be diagnosed and treated in dedicated chronic care clinics in two large regions (one in Tanzania and one in Uganda).
- Reorganise HIV clinics into chronic care clinics in 2 large regions (different from the above) so that they can diagnose and treat all three conditions: HIV, diabetes and hypertension.
- Decentralise care from health facilities to community posts for patients stable on treatment.
- Evaluate these approaches in terms of acceptability (by patients and community), number of patients treated and retained, clinical outcomes, costs of integrated care delivery, and cost-effectiveness (compared to current standard care).
- Use the data generated to develop national and global clinical guidelines for the provision of diabetes and hypertension care in low-resource settings.
- Describe the challenges faced by health services in delivering the integration models and disseminate this knowledge to improve practices and facilitate further scale up.
- Develop sustainable partnerships between researchers, government policy makers, public-private partnerships to facilitate the scale-up nationally.
- Disseminate the knowledge generated to facilitate effective control of diabetes and hypertension in low-resource settings.
Impact
This project is expected to catalyse the scale up of diabetes and hypertension services in the two countries and beyond. The model could also be replicated for other disease conditions, facilitating universal access to care and health coverage and optimizing the use of resources.
Total funding
€ 4.2 million
Nuestro equipo
Equipo ISGlobal
-
Jeffrey Lazarus Associate Research Professor y codirector del Programa de Infecciones Víricas y Bacterianas
-
Camila Picchio Predoctoral Fellow
Otros proyectos
Ver proyectos pasadosANTICOV
Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19
COMBACTE
Combatiendo la Resistencia Bacteriana en Europa
Evaluación de estrategias para la erradicación de la enfermedad del Pian
Erradicación del Pian
Novel Marine Biomolecules against Biofilm (NoMorFilm)
Application to medical devices
COMBACTE-CARE
Combatting Bacterial Resistance in Europe - Carbapenem Resistance
Prioritising Antimicrobial Resistance: establishing an interdisciplinary International Research Partnership to tackle an evolving global health threat
An interdisciplinary International Research Partnership to tackle an evolving global health threat
Development of new metal-antibiotics against pathogens causing chronic infections in patients with cystic fibrosis.
New metal-antibiotics for patients with cystic fibrosis
HU-MEN (High frequency Ultrasound-based MENingitis screening)
Non-invasive ultrasound-based screening for meningitis: Proof-of concept in infants
Xpatial-TB
Improved case detection through TB contact risk stratification by Xpert results and spatial parameters in Mozambique
WHIP3TB
Evaluation of the effect of weekly high dose rifapentine and isoniazid (3HP) vs periodic 3HP vs 6H for preventing TB among HIV-positive individuals
New antibacterial agents against 'Acinetobacter baumannii'
Search for new target proteins and use of antibacterial or inhibitory peptides against resistance mechanisms in 'Acinetobacter baumannii'
Desarrollo de nuevos metaloantibióticos frente a patógenos causantes de infecciones crónicas en pacientes con fibrosis quística
VINCI
Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique
AVATAR
Searching the hidden: evaluating dengue, chikungunya and Zika autochthonous transmission in the city of Barcelona.
COVID-PREG
Eficacia de hidroxicloroquina en la prevención de la infección por SARS-CoV-2 y de la gravedad de la enfermedad de COVID-19 durante el embarazo
SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT)
Estudio piloto para evaluar el potencial de la ivermectina para reducir la transmisión de COVID-19
Encuesta serológica Cendea de Cizur
Cendea de Cizur
CoViproteHCt
Projecte de Recerca en Resposta Immunitària i Epidemiologia de Malalties Infeccioses
Conèixer la propagació. Entendre la protecció
AMR DetecTool
A breakthrough device for the rapid detection of antimicrobial resistance
HBV-COMSAVA
Hepatitis B Virus COMmunity Screening and Vaccination in Africans
Stool4TB
Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV
Hep C Free Baleares
Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.
CAPTB
Close the Gap, Increase Access, Provide Adequate Therapy
SAFE (Superbug Awareness For Education)
Second Edition
STREESCO
Strengthening Epidemiological Surveillance in Benin and Burkina Faso for an Effective Response to COVID-19
COVAIR-CAT
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia
TB-RECONNECT
Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status
SToolNIH
Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring
ALIA
Las ciudades y la salud
END-VOC
ENDing COVID-19 Variants Of concern through Cohort studies (END-VOC)
Estudio de la propagación de bacterias y genes de resistencia a los antibióticos en el ciclo integral del agua, en el área metropolitana de Barcelona
Propagación de la resistencia en aguas
Nuevos complejos de oro (III) frente a bacterias multirresistentes
Project Code: DTS21/00004
Desarrollo de dos nuevas estrategias terapéuticas (inhibidores de bombas de expulsion y ARN antisentido) activos frente a bacterias mutliresistentes
Más allá de la supresión vírica del VIH: un cuarto noventa para mejorar la salud de personas viviendo con el VIH en España
Project Code: PI20/01654
VH-COMSAVAC
Viral Hepatitis COMmunity Screening, Vaccination, and Care
TrackU
Una herramienta para conocer tu riesgo de contagio de SARS-CoV-2
ENDÈMIC
Community knowledge generation through scientific culture, urban ecology and art
CARE
Linkage and retention in care following home-based HIV testing serosurveys in Manhiça District, Southern Mozambique
METRO
Measuring community prevalence among HIV exposed children in rural Southern Mozambique
MAMAH
Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women
PreFIT
Predicting the Future: Incipient Tuberculosis
2G Color Plates
2nd Generation Color Agar Plates to Diagnose MDR-Tuberculosis: a Prospective Pilot Study