- June 2019- May 2024
- Isabelle Thierry Chef
- Horizon2020 (EC)
- Página web
The use of radiation for medical diagnosis and treatment procedures has had a major impact on the survival of paediatric patients. Although the benefits of these techniques largely outweigh the risks, there is a need to better understand the long-term health effects of such exposures in order to optimise treatment plans in these young patients and reduce the risk of late toxicities.
HARMONIC aims at better understanding the long-term health effects of medical exposure to ionising radiation in children, specifically those undergoing radiotherapy for cancer or X-ray guided imaging for cardiac interventions.
The European-funded project consortium is composed of 24 European partners and led by ISGlobal.
By building European cohorts and registries for long-term follow up of paediatric patients, we aim to:
- Investigate the late health effects in children undergoing modern radiotherapy (including proton therapy)
- Investigate development of cancer in children exposed to X-ray guided imaging for treatment of cardiac disorders
- Provide the medical and radiation protection (RP) communities with tools for long-term follow-up of children exposed to medical ionising radiation.
- Improve estimates of radiation doses received by different organs in the body during these procedures
- Investigate possible mechanisms that may lead to the development of cancer and vascular diseases in these patients later in life
- Establish recommendations to optimise these techniques and further reduce radiation doses received by children undergoing X-ray guided imaging and radiotherapy
HARMONIC will provide much-needed information on the effects of low to moderate doses of radiation on humans and help improve radiological protection in medicine.
The 5-year project is based on building a close relationship with clinicians (paediatric oncologists and cardiologists), sociologists, and patients, which will ensure the study is relevant not only in terms of clinical effectiveness but also in terms of patient care and quality of life.
7 million €
Otros proyectosVer proyectos pasados
Estudio multi-caso control poblacional, incluyendo tumores de alta incidencia en España
Novel tools for integrating early-life environmental exposures and child health across Europe
Early Genetics Growth/Early Genetics and Lifecourse Epidemiology
Pregnancy and Childhood Epigenetics
Early-life stressors and LifeCycle health
Network on the Coordination and Harmonisation of European Occupational Cohorts
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement
Signs of Early Adaptation to Climate Change
Cohorte Covid-19 en Cataluña
Advancing Tools for Human Early Lifecourse Exposome Research and Translation
Cohorte de COVID-19 en España: dinámica social, salud mental y desigualdades
A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health
An integrative strategy of testing systems for identification of EDs related to metabolic disorders
EXposome Powered tools for healthy living in urbAN SEttings
Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics
Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility
Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development
El impacto de la exposición al metaboloma de esteroides materno-fetales en el crecimiento infantil y los resultados neurológicos (IGRO)
Project Code: PI21/01269
The role of seafood and nut consumption on human neurodevelopment from pregnancy to adolescence
ALTER - Contaminación del aire, microbiota intestinal y neurodesarrollo en los primeros 24 meses de vida
Project Code: PI21/01278
¿Es mejor consumir el agua de grifo si queremos reducir la exposición a nano/micropláticos?
Urban and social environment and childhood obesity – a natural moving2health experiment
Planificación urbana, medio ambiente y salud
Characterization of Oral NMP Exposure
In-Depth Genomics and Cross-Omics Analysis for Undiagnosed Rare Diseases on a User-Friendly Collaborative Platform
An Exposome Approach to Urban Health: Individualized Environmental Exposure Assessment in an Adults Population Cohort Study (GCAT)
Digital Twins Enabled Indoor Air Quality Management for Healthy Living
Infection acquisition in early life and health outcomes in childhood - MARATO TV3
The Urban Burden of Disease Estimation for POLICY Making
Exposición prenatal a sustancias poli y perfluoradas en agua de consumo y neurodesarrollo en el inicio de la vida
Project Code: PI20/00829
Project Code: PI20/01116
Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease
Drinking Water in Barcelona: Sustainability and Health Impact Assessment
Exposome Project for Health and Occupational Research