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Climate, Air Pollution, Nature and Urban Health

Environment and Health over the Lifecourse

Global Viral and Bacterial Infections

Malaria and Neglected Parasitic Diseases

Maternal, Child and Reproductive Health

Iniciativas clave del programa Severo Ochoa - Título

Research Hubs

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Implementation Science Hub

Research

Implementation Science Hub

Photo: Ben White / Unsplash

Implementation Science (ImpSci) is a broad scientific discipline whose goal is to identify the barriers and facilitators to large-scale deployment of evidence-based interventions in routine practice, either during the implementation planning stage or to address deficiencies once deployment within the health system has already started. As such, research questions normally focus on the “how” (effective implementation) rather than the “what” (evidence-based interventions), and aim to reduce the “know-do-gap” and facilitate effective translation of research into policy and practice.

Using a broader definition, ImpSci can also include other related areas such as:

Health impact assessments conducted to assess the potential scenarios of the effects of a policy or program on the health of a population.
Impact evaluations to assess the effectiveness of interventions after programmatic deployment.
Optimization studies to inform which are the most suitable interventions or implementation strategies to deploy in different settings.

ImpSci generates the evidence needed by health programs to plan or improve their policies and large-scale implementation, addressing questions comprising both the health system and the community, with the aim of improving effectiveness, efficiency, quality, access, scale-up and/or long-term sustainability using scientifically valid methods.

In summary, ImpSci is necessary to bridge the gap between etiologic/efficacy research and public health/individual interventions in “real-world context”.

Aims of the Implementation Science Hub

To increase ISGlobal’s research portfolio and output on ImpSci.
To facilitate collaboration on ImpSci within ISGlobal and with external partners.
To promote research excellence and methodological innovation related to ImpSci.
To promote long-lasting interdisciplinary collaborations with other partners.
To promote policy translation of ImpSci results.
To provide training related to ImpSci methods.
To attract and train new talent in ImpSci.
To promote the international visibility of ISGlobal’s work on ImpSci through research, conferences and courses.

ISGlobal’s mission is to work on both research and translation with the application of knowledge, and the creation of the initiatives responded to the need of facilitating this translation. The creation of an “ISGlobal Implementation Science Hub” would complement the existing structure with the aim of promoting implementation research and thus facilitating the uptake and generalization of evidence-based interventions for health.

General Bibliography

Implementation Science Outcomes → Proctor et al. Outcomes for implementation Research: Conceptual distinctions, measurement challenges, and Research agenda. Adm Policy Ment Health (2011)
Peters, D. H., Tran, N. T., & Adam, T. (2013). Implementation research in health: a practical guide. World Health Organization.
Theobald, S., Brandes, N., Gyapong, M., El-Saharty, S., Proctor, E., Diaz, T., Wanji, S., Elloker, S., Raven, J., Elsey, H. and Bharal, S., 2018. Implementation research: new imperatives and opportunities in global health. The Lancet.Health Policy Volume 392, Issue 10160, P2214-.
Nilsen, P. (2015). Making sense of implementation theories, models and frameworks. Implementation Science, 10(1), 53.
Peters, D. H., Adam, T., Alonge, O., Agyepong, I. A., & Tran, N. (2013). Implementation research: what it is and how to do it. British Medical Journal, 347, f6753.
Damschroder, L (2020). Clarity out of chaos: Use of theory in implementation research. Psychiatry Research, Volume 283
Bauer, M and Kirchner, Johann. (2020) Implementation science: What is it and why should I care? Psychiatry Res 2020 Jan
Allotey, P., Reidpath, D. D, & Ghalib, H., Pagnoni, F., & Skelly, W. C. (2008). Efficacious, effective, and embedded interventions: Implementation research in infectious disease control. BMC Public Health 8 (843).
TDR/WHO IMPLEMENTATION RESEARCH TOOLKIT → https://adphealth.org/irtoolkit/

Theories, models and frameworks on ImpSci

Determinants of implementation (studing the context) → Damschroder et al. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science (CFIR) . Imp.Science (2009)
Glasgow et al. The RE-AIM framework for evaluating interventions: what can it tell us about approaches to chronic illness management?. Patient education and counseling (2001)
Process model that specifies relationships between determinants of implementation, implementation strategies, the mechanism of action resulting from the strategies, and the implementation and clinical outcomes affected. → Smith et al. The implementation Research Logic Model: a method for planning, executing, reporting and synthesizing implementation projects. Imp.Science (2020)
Powell et al. A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project. Imp.Science (2015)
Fernández et al. Implementation Mapping: Using Intervention Mapping to Develop Implementation Strategies. Front. Public Health (2019)
A framework for scaling up interventions → Pierre M Barker, Amy Reid, Marie W Schall (2016). A framework for scaling up health interventions: lessons from large-scale improvement initiatives in Africa. Implement Sci. 2016 Jan 29;11:12.

Online Tools

Online Free Courses

Other ImpSci Hubs

Hub Coordinators

Laura De La Fuente Postdoctoral Researcher
Caterina Guinovart Senior Advisor for Research and Implementation on malaria elimination
Hub Team

Matiana González Coordinator of the Malaria Elimination Initiative
Mònica Ubalde Postdoctoral Researcher
Fiona Vande Velde Visiting Researcher
Hub Committee

Carolyn Daher Coordinator of the Urban Planning, Environment and Health Initiative
Stella Evangelidou Postdoctoral Fellow
Anne-Sophie Gresle Public and Patient Involvement & Patient Experience Manager
Jeffrey Lazarus Research Professor
MARIA MAIXENCHS Staff Scientist
DENISE NANICHE Scientific Director
Mark J Nieuwenhuijsen Research Professor, Director of the Urban Planning, Environment and Health Initiative, and Head of the Climate, Air Pollution, Nature and Urban Health Programme
Leire Pajín Global Development Director
Regina Rabinovich Director of the Malaria Elimination Initiative
Davide Rasella Associate Research Professor and Head of the Health Impact Assessment Group
ANA REQUENA Assistant Research Professor
Elisa Sicuri Associate Research Professor

Projects

See Past Projects

MULTIPLY

MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention

VINCI

Optimizing provider-initiated HIV testing, linkage, and retention in care in the district of Manhiça, Mozambique

ADAM

Malaria mass and focal drug administration to advance malaria elimination in Mozambique: accelerating programmatic implementation and policy translation

Matiana González

The R21 Malaria Vaccine : Standing On the Shoulders of Giants

WHO gives the green light to a second malaria vaccine hoping to solve the serious supply problems affecting the earlier vaccine. [This text...

Research, Malaria Elimination 04.10.2023

MARIA TUSELL

From Knowledge to Action: Towards Enhanced Malaria Elimination Strategies

What to do when you know that an intervention is useful and valuable, but you are not sure what strategy to use so that it reaches everybody in...

Research, Malaria Elimination 11.05.2022

Mònica Ubalde

Safe and Healthy Schools and School Routes: Health Benefits for Children

[This text was written by Mònica Ubalde, Carolyn Daher, Mireia Gascon, Ioar Rivas, Jordi Sunyer and Mark...

Research, Policy & Global Development 28.05.2021

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