Implementation Science Hub

ISGlobal Implementation Science Hub
Photo: Ben White / Unsplash



Implementation Science (ImpSci) is a broad scientific discipline whose goal is to identify the barriers and facilitators to large-scale deployment of evidence-based interventions in routine practice, either during the implementation planning stage or to address deficiencies once deployment within the health system has already started. As such, research questions normally focus on the “how” (effective implementation) rather than the “what” (evidence-based interventions), and aim to reduce the “know-do-gap” and facilitate effective translation of research into policy and practice.

Using a broader definition, ImpSci can also include other related areas such as:

  • Health impact assessments conducted to assess the potential scenarios of the effects of a policy or program on the health of a population.
  • Impact evaluations to assess the effectiveness of interventions after programmatic deployment.
  • Optimization studies to inform which are the most suitable interventions or implementation strategies to deploy in different settings.

ImpSci generates the evidence needed by health programs to plan or improve their policies and large-scale implementation, addressing questions comprising both the health system and the community, with the aim of improving effectiveness, efficiency, quality, access, scale-up and/or long-term sustainability using scientifically valid methods.

In summary, ImpSci is necessary to bridge the gap between etiologic/efficacy research and public health/individual interventions in “real-world context”.

Aims of the Implementation Science Hub

  • To increase ISGlobal’s research portfolio and output on ImpSci.
  • To facilitate collaboration on ImpSci within ISGlobal and with external partners.
  • To promote research excellence and methodological innovation related to ImpSci.
  • To promote long-lasting interdisciplinary collaborations with other partners.
  • To promote policy translation of ImpSci results.
  • To provide training related to ImpSci methods.
  • To attract and train new talent in ImpSci.
  • To promote the international visibility of ISGlobal’s work on ImpSci through research, conferences and courses.

ISGlobal’s mission is to work on both research and translation with the application of knowledge, and the creation of the initiatives responded to the need of facilitating this translation. The creation of an “ISGlobal Implementation Science Hub” would complement the existing structure with the aim of promoting implementation research and thus facilitating the uptake and generalization of evidence-based interventions for health.

Highlighted Projects

(Caterina Guinovart)

(Denise Naniche)

(Clara Menéndez)

(Regina Rabinovich)

(Mònica Ubalde)

Useful Resources

  • Implementation Science Outcomes → Proctor et al. Outcomes for implementation Research: Conceptual distinctions, measurement challenges, and Research agenda. Adm Policy Ment Health (2011)
  • Peters, D. H., Tran, N. T., & Adam, T. (2013). Implementation research in health: a practical guide. World Health Organization.
  • Theobald, S., Brandes, N., Gyapong, M., El-Saharty, S., Proctor, E., Diaz, T., Wanji, S., Elloker, S., Raven, J., Elsey, H. and Bharal, S., 2018. Implementation research: new imperatives and opportunities in global health. The Lancet.Health Policy Volume 392, Issue 10160, P2214-.
  • Nilsen, P. (2015). Making sense of implementation theories, models and frameworks. Implementation Science, 10(1), 53.
  • Peters, D. H., Adam, T., Alonge, O., Agyepong, I. A., & Tran, N. (2013). Implementation research: what it is and how to do it. British Medical Journal, 347, f6753.
  • Damschroder, L (2020). Clarity out of chaos: Use of theory in implementation research. Psychiatry Research, Volume 283
  • Bauer, M and Kirchner, Johann. (2020) Implementation science: What is it and why should I care? Psychiatry Res 2020 Jan
  • Allotey, P., Reidpath, D. D, & Ghalib, H., Pagnoni, F., & Skelly, W. C. (2008). Efficacious, effective, and embedded interventions: Implementation research in infectious disease control. BMC Public Health 8 (843).
  • Determinants of implementation (studing the context) → Damschroder et al. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science (CFIR) . Imp.Science (2009)
  • Glasgow et al. The RE-AIM framework for evaluating interventions: what can it tell us about approaches to chronic illness management?. Patient education and counseling (2001)
  • Process model that specifies relationships between determinants of implementation, implementation strategies, the mechanism of action resulting from the strategies, and the implementation and clinical outcomes affected. → Smith et al. The implementation Research Logic Model: a method for planning, executing, reporting and synthesizing implementation projects. Imp.Science (2020)
  • Powell et al. A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) project. Imp.Science (2015) 
  • Fernández et al. Implementation Mapping: Using Intervention Mapping to Develop Implementation Strategies. Front. Public Health (2019)
  • A framework for scaling up interventionsPierre M Barker, Amy Reid, Marie W Schall (2016). A framework for scaling up health interventions: lessons from large-scale improvement initiatives in Africa. Implement Sci. 2016 Jan 29;11:12. 


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