Research Programmes
Urban Planning, Environment and Health

EXPOsOMICS

Duration
2012-2016
Coordinator
Paolo Vineis (Imperial College, London)
Funded by
European Comission
Website
http://www.exposomicsproject.eu
This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero.

Although environmental (i.e. non-genetic) exposures account for the majority of diseases currently there is no standard or systematic way to measure the influence of environmental exposures on health. This project will move the field forward by developing a personal exposure monitoring (PEM) system (including sensors, smartphones, geo-referencing, satellites) and collect data on individual external exposome as well as analysing biological samples (internal markers of external exposures) using multiple “omic” technologies. The search for the relationships between external exposures (as measured by PEM, which has not previously been used in large scale studies) and global profiles of molecular features (as measured by omics) in the same individuals constitutes a novel advance towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as ‘exposome-wide association studies’ (EWAS).

The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease.

Our Team

Principal Investigator (PI)

  • Marius Joannes Nieuwenhuijsen
    Marius Joannes Nieuwenhuijsen

Our Team

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Other projects

See Past Projects

CHAI

Cardiovascular Health effects of Air pollution in Andhra Pradesh, India

ESAIRE

Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality

iMAP Barcelona

The international Mind, Activities and urban Places in Barcelona study (iMAP Barcelona study): Building the evidence base on the relationships between environment, active living and cognitive health

EARLY-ADAPT

Signs of Early Adaptation to Climate Change

ACTIVID

Impact of the health crisis due to COVID-19 on Physical Activity and Mental Health in Spain

REMEDHY

Researching Environments that Magnify Health Everyday

ELHNA

Exposures to light pollution and heat, and neurodevelopment in adolescents. Project Code: PI20/01695

ONES

Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility

RECETAS

Re-imagining Environments for Connection and Engagement: Testing Actions for Social Prescribing in Natural Spaces

CATALYSE

Climate Action To Advance HeaLthY Societies in Europe

MCC-Spain

Population based multicasecontrol study on common tumours in Spain

PROactive

Physical Activity as a Crucial Patient Reported Outcome in COPD

OMEGA-NET

Network on the Coordination and Harmonisation of European Occupational Cohorts

POLLAR

Impact Of Pollution on Asthma and Rhinitis

EPHOR

Exposome Project for Health and Occupational Research

CORSAIR

Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors

VEIS

Leveraging the European Genome-Phenome Archive (EGA) for Industry and Society

Mobilise-D

Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

COVICAT

Cohorte Covid-19 en Cataluña

AiguaBCN

Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing

Fotovoz

Las Voces de los Afectados por la Nefropatía Mesoamericana

CALMA

Co-created educational programme for dyspnea-bearing patients and their caregivers

Cancer-Watch

Risk of colorectal and breast cancer with widespread drinking water chemical contaminants

CONTENT

Cohort of COVID-19 in Spain: social dynamics, mental health and inequalities

EXPANSE

EXposome Powered tools for healthy living in urbAN SEttings

COVAIR-CAT

Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia

iGenCO

In-Depth Genomics and Cross-Omics Analysis for Undiagnosed Rare Diseases on a User-Friendly Collaborative Platform

CityExposomeCat

An Exposome Approach to Urban Health: Individualized Environmental Exposure Assessment in an Adults Population Cohort Study (GCAT)

TwinAir

Digital Twins Enabled Indoor Air Quality Management for Healthy Living

UBDPOLICY

The Urban Burden of Disease Estimation for POLICY Making

TOLIFE

Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease

EGG/EAGLE

Early Genetics Growth/Early Genetics and Lifecourse Epidemiology

PACE

Pregnancy and Childhood Epigenetics

APACHE

Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe

LIFECYCLE

Early-life stressors and LifeCycle health

ATHLETE

Advancing Tools for Human Early Lifecourse Exposome Research and Translation

MOOD-COVID

Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic

EUCAN-Connect

A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health

OBERON

An integrative strategy of testing systems for identification of EDs related to metabolic disorders

The Lungfit Project

Socioeconomic Status, Physical Activity, and Respiratory Health in Pregnant Women, Children, and Adolescents

ExPEC-TEEN

Prenatal Exposure to Environmental Pollutants and Metabolic and Cardiovascular Health of the Teenagers

AURORA 2021

Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics

HELIX-NAFLD

Developmental origins of child liver injury: the effect of early life environmental exposures

UrbaMet

Entorno Urbano y Salud Cardiometabólica desde el Nacimiento hasta la Adolescencia

NutriPROGRAM

Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways

AIR-NB

Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development

FRONTIER

Traffic-Related Air Pollution and Birth Weight: the Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status

The APBO Project

Air Pollution and Birth Outcomes: Windows of Exposure and Health and Economic Impact Assessment

INMA-Ado-Sueño

Radio Frequency Electromagnetic Fields, Noise, and Sleep Disorders in Adolescence

ANSES HyPAXE

Prenatal Exposure to a Family of Short Half-Life Endocrine Disruptors, Dysregulation of the Hypothalamic–Pituitary–Adrenal Axis and Potential Implication for Child Neurodevelopment at Early Age

EXPO-ENFANTS

Caractérisation des usages et de l’exposition aux radiofréquences induite par les dispositifs de communication mobiles chez les enfants

Lilli

Light at Night Exposure and Sleep Quality

EMBRYORAD

Radiofrequency Electromagnetic Fields, Other Environmental Factors, and Development of the Embryo and Fetus

NutinBrain

The role of seafood and nut consumption on human neurodevelopment from pregnancy to adolescence

UrbanKids

Urban and social environment and childhood obesity – a natural moving2health experiment