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Climent Casals-Pascual

Climent Casals-Pascual

Associate Research Professor Malaria, Resistències a antibiòtics, Resistències a antibiòtics, VIH / SIDA i TB, Infeccions Virals i Bacterianes

Climent Casals is an independent clinical researcher with 9 years experience as principal investigator in biomarker discovery infectious diseases with extensive field experience (more than 4 years based in African countries). He has led a research group at the University of Oxford since 2008 and he is currently working as a consultant in Medical Microbiology at the Hospital Clinic i Provincial in Barcelona and hold an Honorary Consultant Contract in Medical Microbiology at the John Radcliffe Hospital in Oxford (UK). He obtained his DPhil degree at the University of Oxford (2004). Climent Casals has designed and conducted clinical and laboratory studies in the UK and in sub-Saharan Africa (Tanzania, Kenya,and The Gambia) and he has expertise in epidemiology, clinical research, proteomics, statistical analysis and systems biology.

Lines of Research

  • Sepsis
  • Malaria
  • Biomarkers
  • Antimicrobial  Stewardship

Main Publications

  • Discovery and validation of biomarkers to guide clinical management of pneumonia in African children. Clinical Infectious Diseases 58 (12), 1707-1715. Honglei Huang, Readon C Ideh, Evelyn Gitau, Marie L Thézénas, Muminatou Jallow, Bernard Ebruke, Osaretin Chimah, Claire Oluwalana, Henri Karanja, Grant Mackenzie, Richard A Adegbola, Dominic Kwiatkowski, Benedikt M Kessler, James A Berkley, Stephen RC Howie, Climent Casals-Pascual
  • PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection. Journal of proteome research 12 (3), 1211-1222. Marie L Theézeénas, Honglei Huang, Madi Njie, Abhinay Ramaprasad, Davis C Nwakanma, Roman Fischer, Katalin Digleria, Michael Walther, David J Conway, Benedikt M Kessler, Climent Casals-Pascual.
  • Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis. The Lancet  372 (9649), 1545-1554. Serign J Ceesay*, Climent Casals-Pascual*, Jamie Erskine, Samuel E Anya, Nancy O Duah, Anthony JC Fulford, Sanie SS Sesay, Ismaela Abubakar, Samuel Dunyo, Omar Sey, Ayo Palmer, Malang Fofana, Tumani Corrah, Kalifa A Bojang, Hilton C Whittle, Brian M Greenwood, David J Conway * First joint
  • High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria. Proceedings of the National Academy of Sciences 105 (7), 2634-2639 Climent Casals-Pascual, Richard Idro, Nimmo Gicheru, Samson Gwer, Barnes Kitsao, Evelyn Gitau, Robert Mwakesi, David J Roberts, Charles RJC Newton
  • Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo. Blood 108 (8), 2569-2577. Climent Casals-Pascual, Oscar Kai, Joyce OP Cheung, Senani Williams, Brett Lowe, Mike Nyanoti, Thomas N Williams, Kathryn Maitland, Malcolm Molyneux, Charles RJC Newton, Norbert Peshu, Suzanne M Watt, David J Roberts