Duración
2012-2016
Coordinador
Paolo Vineis (Imperial College, London)
Financiadores
Comisión Europea

This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero.

Although environmental (i.e. non-genetic) exposures account for the majority of diseases currently there is no standard or systematic way to measure the influence of environmental exposures on health. This project will move the field forward by developing a personal exposure monitoring (PEM) system (including sensors, smartphones, geo-referencing, satellites) and collect data on individual external exposome as well as analysing biological samples (internal markers of external exposures) using multiple “omic” technologies. The search for the relationships between external exposures (as measured by PEM, which has not previously been used in large scale studies) and global profiles of molecular features (as measured by omics) in the same individuals constitutes a novel advance towards the development of "next generation exposure assessment" for environmental chemicals and their mixtures. The linkage with disease risks opens the way to what are defined here as ‘exposome-wide association studies’ (EWAS).

The ultimate goal is to use the new tools in risk assessment and in the estimation of the burden of environmental disease.

Nuestro equipo

Investigador principal (IP)

  • Marius Joannes Nieuwenhuijsen
    Marius Joannes Nieuwenhuijsen

Equipo ISGlobal

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Otros proyectos

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CHAI

Cardiovascular Health effects of Air pollution in Andhra Pradesh, India

ESAIRE

Engaging Citizens in Science: Promoting the Viability of Participatory Sensing for Monitoring Air and Environmental Quality

iMAP Barcelona

Estudio Internacional de la Mente, Actividades y Entornos Urbanos en Barcelona

EARLY-ADAPT

Signs of Early Adaptation to Climate Change

ACTIVID

Impacto de la crisis sanitaria de la COVID-19 en la Actividad Física y la Salud Mental en España

REMEDHY

Researching Environments that Magnify Health Everyday

ELHNA

Exposures to light pollution and heat, and neurodevelopment in adolescents

ONES

Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility

RECETAS

Re-imagining Environments for Connection and Engagement: Testing Actions for Social Prescribing in Natural Spaces

MCC-Spain

Estudio multi-caso control poblacional, incluyendo tumores de alta incidencia en España

ALEC

Aging Lungs in European Cohorts

PROactive

Physical Activity as a Crucial Patient Reported Outcome in COPD

QUALI-VERD

Social and environmental determinants of physical activity in patients with chronic obstructive pulmonary disease (COPD): a qualitative and quantitative epidemiological study

OMEGA-NET

Network on the Coordination and Harmonisation of European Occupational Cohorts

POLLAR

Impact Of Pollution on Asthma and Rhinitis

CORSAIR

Severe respiratory failure in COVID-19: clinical, biological and imaging risk factors

VEIS

Valorización del Archivo Europeo del Genomas y Fenomas (EGA) para la Industria y la Sociedad

Mobilise-D

Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

COVICAT

Cohorte Covid-19 en Cataluña

AiguaBCN

Exposure to emerging contaminants in drinking water in Barcelona potentially liked to chronic diseases and wellbeing

Fotovoz

Las Voces de los Afectados por la Nefropatía Mesoamericana

CALMA

Co-created educational programme for dyspnea-bearing patients and their caregivers

Cancer-Watch

Risk of colorectal and breast cancer with widespread drinking water chemical contaminants

CONTENT

Cohorte de COVID-19 en España: dinámica social, salud mental y desigualdades

EXPANSE

EXposome Powered tools for healthy living in urbAN SEttings

COVAIR-CAT

Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia

APACHE

Air Pollution, Autism spectrum disorders, and brain imaging in CHildren amongst Europe

LIFECYCLE

Early-life stressors and LifeCycle health

ATHLETE

Advancing Tools for Human Early Lifecourse Exposome Research and Translation

MOOD-COVID

Pre- and post-natal Maternal mental health and newbOrn neurOdevelopment during the COVID-19 panDemic

EUCAN-Connect

A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health

OBERON

An integrative strategy of testing systems for identification of EDs related to metabolic disorders

The Lungfit Project

Socioeconomic Status, Physical Activity, and Respiratory Health in Pregnant Women, Children, and Adolescents

ExPEC-TEEN

Prenatal Exposure to Environmental Pollutants and Metabolic and Cardiovascular Health of the Teenagers

AURORA 2021

Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics

HELIX-NAFLD

Developmental origins of child liver injury: the effect of early life environmental exposures

UrbaMet

Entorno Urbano y Salud Cardiometabólica desde el Nacimiento hasta la Adolescencia

NutriPROGRAM

Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways

AIR-NB

Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development

FRONTIER

Traffic-Related Air Pollution and Birth Weight: the Roles of Noise, Placental Function, Green Space, Physical Activity, and Socioeconomic Status

The APBO Project

Air Pollution and Birth Outcomes: Windows of Exposure and Health and Economic Impact Assessment

ANSES HyPAXE

Prenatal Exposure to a Family of Short Half-Life Endocrine Disruptors, Dysregulation of the Hypothalamic–Pituitary–Adrenal Axis and Potential Implication for Child Neurodevelopment at Early Age